Evidence map›Paper›PMID 25050615›Full record

ArticleEpidemiology and infection2015

Molecular epidemiology of tuberculosis in Cambodian children.

K Schopfer, H L Rieder, J F Steinlin-Schopfer, D van Soolingen, T Bodmer, Y Chantana, P Studer, D Laurent, M Zwahlen, B Richner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Distribution and origins ofMicrobial genomics · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K SchopferInstitute of Infectious Diseases,University of Bern,Switzerland.
H L RiederInternational Union Against Tuberculosis and Lung Disease, Paris,France.
J F Steinlin-SchopferInstitute of Infectious Diseases,University of Bern,Switzerland.
D van SoolingenNational Mycobacteria Reference Laboratory,National Institute for Public Health and the Environment,Bilthoven,The Netherlands.
T BodmerInstitute of Infectious Diseases,University of Bern,Switzerland.
Y ChantanaKantha Bopha Foundation, Phnom Penh,Cambodia.
P StuderKantha Bopha Foundation, Phnom Penh,Cambodia.
D LaurentKantha Bopha Foundation, Phnom Penh,Cambodia.
M ZwahlenInstitute of Social and Preventive Medicine,University of Bern,Switzerland.
B RichnerKantha Bopha Foundation, Phnom Penh,Cambodia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SUMMARY We analysed Mycobacterium tuberculosis strains from children, hospitalized from January 2004 to July 2008 in the largest paediatric hospital complex in Cambodia. Specimens were tested for drug susceptibility and genotypes. From the 260 children, 161 strains were available. The East African-Indian genotype family was the most common (59.0%), increasing in frequency with distance from the Phnom Penh area, while the frequency of the Beijing genotype family strains decreased. The drug resistance pattern showed a similar geographical gradient: lowest in the northwest (4.6%), intermediate in the central (17.1%), and highest in the southeastern (30.8%) parts of the country. Three children (1.9%) had multidrug-resistant tuberculosis. The Beijing genotype and streptomycin resistance were significantly associated (P < 0.001). As tuberculosis in children reflects recent transmission patterns in the community, multidrug resistance levels inform about the current quality of the tuberculosis programme.

Indexed as

AdolescentAntitubercular AgentsCambodiaChildChild, PreschoolDNA, BacterialDrug Resistance, Multiple, BacterialFemaleGenotypeHumansInfantInfant, NewbornIsoniazidMaleMicrobial Sensitivity TestsMycobacterium tuberculosisAntitubercular AgentsDNA, BacterialIsoniazidRifampinStreptomycintuberculosis (TB)

Identifiers

PMID25050615
PMCPMC9507131

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.