Evidence map›Paper›PMID 25050596›Full record

ArticleThe Journal of investigative dermatology2015

Topical photodynamic therapy induces systemic immunosuppression via generation of platelet-activating factor receptor ligands.

Matheus Ferracini, Ravi P Sahu, Kathleen A Harrison, Robert A Waeiss, Robert C Murphy, Sonia Jancar, Raymond L Konger, Jeffrey B Travers

Abstract readLetter
In one paragraph

Article in The Journal of investigative dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
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  7. Review
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  13. Implications of Aspirin for Melanoma Treatment: A Short Perspective.Journal of molecular genetics and medicine · 2017
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matheus FerraciniDepartment of Immunology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo, Brazil.
Ravi P SahuDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Laboratory Medicine, Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kathleen A HarrisonDepartment of Pharmacology, University of Colorado Health Sciences Center, Aurora, Colorado, USA.
Robert A WaeissDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Robert C MurphyDepartment of Pharmacology, University of Colorado Health Sciences Center, Aurora, Colorado, USA.
Sonia JancarDepartment of Immunology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo, Brazil.
Raymond L KongerDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Laboratory Medicine, Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jeffrey B TraversDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA; The Richard L. Roudebush V.A. Medical Center, Indianapolis, Indiana, USA. Electronic address: jtravers@iupui.edu.

Funding

Platelet Activating Factor and Epidermic CytotoxicityR01HL062996 · NHLBI · WRIGHT STATE UNIVERSITY · PI TRAVERS, JEFFREY B. · 1999 to 2023
$7.2M
Wounding Therapy and PhotocarcinogenesisR01AG048946 · NIA · WRIGHT STATE UNIVERSITY · PI SPANDAU, DAN F, TRAVERS, JEFFREY B. · 2014 to 2024
$2.9M
Mechanisms of photocarcinogenesis in geriatric skinR01ES020866 · NIEHS · INDIANA UNIVERSITY INDIANAPOLIS · PI SPANDAU, DAN F, TRAVERS, JEFFREY B. · 2012 to 2016
$1.7M
Environmental pro-oxidative stressors and immunosuppressionK22ES023850 · NIEHS · WRIGHT STATE UNIVERSITY · PI SAHU, RAVI PRAKASH · 2014 to 2016
$488k
Oxidized Lipids and UV ImmunosuppressionI01BX000853 · VA · RLR VA MEDICAL CENTER · PI Jeffrey B. Travers · 2011 to 2026
–
BLRD VA I01 BX000853NHLBI NIH HHS R01 HL062996NIA NIH HHS R01 AG048946NIEHS NIH HHS K22 ES023850NIEHS NIH HHS R01 ES020866
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PhotochemotherapyAnimalsCell LineHumansImmune ToleranceKeratinocytesKeratosis, ActinicLigandsMicePlatelet Membrane GlycoproteinsReceptors, G-Protein-CoupledSkin NeoplasmsLigandsplatelet activating factor receptorPlatelet Membrane GlycoproteinsReceptors, G-Protein-Coupled

Identifiers

PMID25050596
PMCPMC4268233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.