Evidence map›Paper›PMID 25050351›Full record

ReviewBioMed research international2014

MR imaging findings in alcoholic and nonalcoholic acute Wernicke's encephalopathy: a review.

Gaetana Manzo, Angela De Gennaro, Attilio Cozzolino, Antonietta Serino, Giacomo Fenza, Andrea Manto

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 2 syntheses or guidelines pooled it, 162 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Novel Magnetic Resonance Imaging Findings of Bilaterally Symmetrical Lesions in a Dog With Concomitant Granulomatous Meningoencephalitis and Necrotizing Encephalitis.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gaetana ManzoDepartment of Biomorphological and Functional Sciences, University of Naples "Federico II," Via Sergio Pansini 5, 80131 Naples, Italy.
Angela De GennaroDepartment of Biomorphological and Functional Sciences, University of Naples "Federico II," Via Sergio Pansini 5, 80131 Naples, Italy.
Attilio CozzolinoDepartment of Neuroradiology, Umberto I Hospital, Viale San Francesco 2, Nocera Inferiore, 84014 Salerno, Italy.
Antonietta SerinoDepartment of Neuroradiology, Umberto I Hospital, Viale San Francesco 2, Nocera Inferiore, 84014 Salerno, Italy.
Giacomo FenzaDepartment of Neuroradiology, Umberto I Hospital, Viale San Francesco 2, Nocera Inferiore, 84014 Salerno, Italy.
Andrea MantoDepartment of Neuroradiology, Umberto I Hospital, Viale San Francesco 2, Nocera Inferiore, 84014 Salerno, Italy.
Policlinico Umberto I · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wernicke's encephalopathy (WE) is a severe neurological syndrome caused by thiamine (vitamin B1) deficiency and clinically characterized by the sudden onset of mental status changes, ocular abnormalities, and ataxia. Apart from chronic alcoholism, the most common cause of WE, a lot of other conditions causing malnutrition and decreasing thiamine absorption such as gastrointestinal surgical procedures and hyperemesis gravidarum must be considered as predisposing factors. Due to its low prevalence and clinical heterogeneity, WE is often misdiagnosed, leading to persistent dysfunctions and, in some cases, to death. Nowadays, MR imaging of the brain, showing T2 and FLAIR hyperintensities in typical (thalami, mammillary bodies, tectal plate, and periaqueductal area) and atypical areas (cerebellum, cranial nerve nuclei, and cerebral cortex), is surely the most important and effective tool in the diagnostic assessment of WE. The aim of this paper is to propose a state of the art of the role of MR imaging in the early diagnosis of this complex disease.

Indexed as

Magnetic Resonance ImagingAlcoholismDiffusion Magnetic Resonance ImagingHumansPrognosisWernicke Encephalopathy

Identifiers

PMID25050351
PMCPMC4094710
OpenAlexW2149941891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.