Evidence map›Paper›PMID 25050337›Full record

Trial reportBioMed research international2014

Myorelaxant effect of bee venom topical skin application in patients with RDC/TMD Ia and RDC/TMD Ib: a randomized, double blinded study.

Aleksandra Nitecka-Buchta, Piotr Buchta, Elżbieta Tabeńska-Bosakowska, Karolina Walczyńska-Dragoń, Stefan Baron

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02101632 (Myorelaxant Effect of Bee Venom), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02101632 nacompletednot on this map

Myorelaxant Effect of Bee Venom(BV) Topical Skin Application in Patients With Research Diagnostic Criteria/Temporomandibular Disorder Ia and Ib (RDC/TMD) Randomized, Double Blinded Study

TypeinterventionalSponsorMedical University of SilesiaRan2014 to 2014Enrolled79ConditionsOther Disorders of Muscle in Diseases Classified ElsewhereArmsBee Venom Ointment, Vaseline Ointment
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Immunology of Bee Venom.Clinical reviews in allergy & immunology · 2018
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aleksandra Nitecka-BuchtaDepartment of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.ORCID 0000-0002-0322-2130
Piotr BuchtaDepartment of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.ORCID 0000-0001-8725-000X
Elżbieta Tabeńska-BosakowskaDepartment of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.ORCID 0000-0001-9857-3170
Karolina Walczyńska-DragońDepartment of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.ORCID 0000-0003-3066-7765
Stefan BaronDepartment of Orthodontics and Temporomandibular Joint Dysfunction, Medical University of Silesia in Katowice, plac Traugutta 2, 41-800 Zabrze, Poland.
Medical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was the evaluation of myorelaxant action of bee venom (BV) ointment compared to placebo. Parallel group, randomized double blinded trial was performed. Experimental group patients were applying BV for 14 days, locally over masseter muscles, during 3-minute massage. Placebo group patients used vaseline for massage. Muscle tension was measured twice (TON1 and TON2) in rest muscle tonus (RMT) and maximal muscle contraction (MMC) on both sides, right and left, with Easy Train Myo EMG (Schwa-medico, Version 3.1). Reduction of muscle tonus was statistically relevant in BV group and irrelevant in placebo group. VAS scale reduction was statistically relevant in both groups: BV and placebo. Physiotherapy is an effective method for myofascial pain treatment, but 0,0005% BV ointment gets better relief in muscle tension reduction and analgesic effect. This trial is registered with Clinicaltrials.gov NCT02101632.

Indexed as

Administration, TopicalAdultBee VenomsDouble-Blind MethodElectromyographyFemaleHumansMaleMasseter MuscleMuscle RelaxationMuscle TonusPain MeasurementPlacebosRestSkinTemporomandibular Joint DisordersBee VenomsPlacebos

Identifiers

PMID25050337
PMCPMC4094729
OpenAlexW2075391259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.