Antitumor properties of two traditional aromatic rice genotypes (Kalijira and Chinigura).

Mohammad Abdul Mannan, Tushar Chandra Sarker, Ahmad Humayan Kabir, Mostafizur Rahman, Mohammad Firoz Alam

Abstract read

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Article in Avicenna journal of phytomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 citing paper in PubMed.

Anticancer L-Asparaginase and Phytoactive Compounds From PlantDose-response : a publication of International Hormesis Society
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5 · Who and what money

Authors and funding

5 authors.

Mohammad Abdul MannanPlant Biotechnology and Microbiology Laboratory, Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh.

Tushar Chandra SarkerPlant Biotechnology and Microbiology Laboratory, Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh.

Ahmad Humayan KabirPlant Biotechnology and Microbiology Laboratory, Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh.

Mostafizur RahmanPlant Biotechnology and Microbiology Laboratory, Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh.

Mohammad Firoz AlamPlant Biotechnology and Microbiology Laboratory, Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMethanol extract of bran and unpolished grain of two traditional aromatic rice genotypes viz. Kalijira and Chinigura were assayed for their activity on the growth and initiation of crown-gall tumors on potato disks. MATERIALS AND

methodsThree Agrobacterium tumefaciens (A. tumefaciens) strain AtSl0105, AtTa0112, and AtAc0114 were used as the tumor forming agent. Collected rice was separated to bran and unpolished grain by different milling processes and made into fine powder before extracting using methanol. Antitumor assay of plant extracts was performed according to standard potato disc bioassay. Disc diffusion assay (Kirby-Bauer Method) was used to screen A. tumefaciens sensitivity test.

resultsThe results demonstrated a high correlation between the ability of aromatic rice to inhibit the initiation and growth of crown-gall tumors on potato disks. Maximum tumor inhibitions were observed against the strain AtSl0105 by Kalijira bran (73.91%) and Chinigura bran (69.56%). Both unpolished grains showed significant effect (Kalijira 57.43%, Chinigura 55.53%) to inhibit the tumor.

conclusionIt can be concluded that aromatic rice (Kalijira and Chinigura) might be a potential source of antitumor agent that can be used for further drug development for tumor treatment.

Indexed as

Antitumor activityTraditional riceTumor inhibitionUnpolished grain

Identifiers

PMID25050299

PMCPMC4103728

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