Evidence map›Paper›PMID 25050220›Full record

ArticleOncoimmunology

Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity.

Christophe Y Calvet, Franck M André, Lluis M Mir

Abstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Immunological evaluation of recombination PRRSV GP3 and GP5 DNA vaccinesFrontiers in cellular and infection microbiology · 2022
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.Molecular therapy : the journal of the American Society of Gene Therapy · 2016
    Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christophe Y CalvetUniv Paris-Sud; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; CNRS; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; Gustave Roussy; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France.
Franck M AndréUniv Paris-Sud; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; CNRS; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; Gustave Roussy; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France.
Lluis M MirUniv Paris-Sud; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; CNRS; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France ; Gustave Roussy; Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses; UMR 8203; Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects for inducing immunity in response to DNA vaccines.

Indexed as

ATPDAMPsdendritic cellelectric pulseselectropermeabilizationgene electrotransferimmunotherapynon-viral gene therapyT lymphocyte

Identifiers

PMID25050220
PMCPMC4077865

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.