Evidence map›Paper›PMID 25050193›Full record

ArticleOncoimmunology

Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak

Manfred B Lutz, Andreas S Baur, Beatrice Schuler-Thurner, Gerold Schuler

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Antibody-drug conjugates come of age in oncology.Nature reviews. Drug discovery · 2023
    Review
  2. Review
  3. Review
  4. Bacteriotherapy in Breast Cancer.International journal of molecular sciences · 2019
    Review
  5. Review
  6. Human regulatory T cells (Treg) and their response to cancer.Expert review of precision medicine and drug development · 2019
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Manfred B LutzInstitute of Virology and Immunobiology; University of Wuerzburg; Wuerzburg, Germany.
Andreas S BaurDepartment of Dermatology; University Hospital Erlangen; Erlangen, Germany.
Beatrice Schuler-ThurnerDepartment of Dermatology; University Hospital Erlangen; Erlangen, Germany.
Gerold SchulerDepartment of Dermatology; University Hospital Erlangen; Erlangen, Germany.
Universitätsklinikum Erlangen · DEInstitute of Virology of the Slovak Academy of Sciences · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ontak

Indexed as

dendritic cellsinterleukin-2 receptorOntakregulatory T cellsT cells

Identifiers

PMID25050193
PMCPMC4091105
OpenAlexW2033626291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.