Evidence map›Paper›PMID 25050133›Full record

ArticleWorld journal of emergency surgery : WJES2014

Predictors of in-hospital mortality and complications in very elderly patients undergoing emergency surgery.

Shaheed Merani, Judd Payne, Raj S Padwal, Darren Hudson, Sandy L Widder, Rachel G Khadaroo

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02825082 (Risk Stratification Tools and Frailty Index for Predicting Perioperative Outcome in Elderly Patients Undergoing Abdominal Emergency Surgery), which is not on this map. Cited by 41 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 5 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02825082 completednot on this mapstarted 2017, after this paper: background citation

Risk Stratification Tools and Frailty Index for Predicting Perioperative Outcome in Elderly Patients Undergoing Abdominal Emergency Surgery

TypeobservationalSponsorUniversity of Roma La SapienzaRan2017 to 2018Enrolled2,200ConditionsSurgery, EmergencyArmsAbdominal emergency surgery
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 5 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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  15. Mortality after abdominal emergency surgery in nonagenarians.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shaheed MeraniDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Judd PayneDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Raj S PadwalDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Darren HudsonDivision of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Sandy L WidderDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada ; Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Rachel G KhadarooDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada ; Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada ; Department of Surgery, University of Alberta, 2D Walter Mackenzie Center, 8440-112 St. NW, Edmonton, Alberta T6G 2B7, Canada.
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWith the increasing aging population demographics and life expectancies the number of very elderly patients (age ≥ 80) undergoing emergency surgery is expected to rise. This investigation examines the outcomes in very elderly patients undergoing emergency general surgery, including predictors of in-hospital mortality and morbidity.

methodsA retrospective study of patients aged 80 and above undergoing emergency surgery between 2008 and 2010 at a tertiary care facility in Canada was conducted. Demographics, comorbidities, surgical indications, and perioperative risk assessment data were collected. Outcomes included length of hospitalization, discharge destination, and in-hospital mortality and morbidity. Multivariable logistic regression was used to identify predictors of in-hospital mortality and complications.

resultsOf the 170 patient admissions, the mean age was 84 years and the in-hospital mortality rate was 14.7%. Comorbidities were present in 91% of this older patient population. Over 60% of the patients required further services or alternate level of care on discharge. American Society of Anesthesiologist Physical Status (ASA) Classification (OR 5.30, 95% CI 1.774-15.817, p = 0.003) and the development of an in-hospital complications (OR 2.51, 95% CI 1.210-5.187, p = 0.013) were independent predictors of postoperative mortality. Chronological age or number of comorbidities was not predictive of surgical outcome.

conclusionsMortality, complication rates and post-discharge care requirements were high in very elderly patients undergoing emergency general surgery. Advanced age and medical comorbidities alone should not be the limiting factors for surgical referral or treatment. This study illustrates the importance of preventing an in-hospital complication in this very vulnerable population. ASA class is a robust tool which is predictive of mortality in the very elderly population and can be used to guide patient and family counseling in the emergency setting.

Indexed as

Acute careElderlyEmergencyMorbidityMortalitySurgery

Identifiers

PMID25050133
PMCPMC4105124
OpenAlexW2170492513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.