Evidence map›Paper›PMID 25049350›Full record

ArticlePediatrics2014

Reducing distress in mothers of children with autism and other disabilities: a randomized trial.

Elisabeth M Dykens, Marisa H Fisher, Julie Lounds Taylor, Warren Lambert, Nancy Miodrag

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03889821 (Does Mindfulness Training Enhance Early Evidence-based Parent-coaching Interventions for Autism Spectrum Disorder?), which is not on this map. Cited by 103 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03889821 nacompletednot on this mapstarted 2015, after this paper: background citation

Does Mindfulness Training Enhance Early Evidence-based Parent-coaching Interventions for Autism Spectrum Disorder?: A Randomized Controlled Trial

TypeinterventionalSponsorVanderbilt University Medical CenterRan2015 to 2018Enrolled63ConditionsAutism Spectrum Disorder, Parents, StressArmsParent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elisabeth M DykensVanderbilt Kennedy Center for Research on Human Development and University Center of Excellence on Developmental Disabilities,Departments of Psychology and Human Development, Pediatrics, and Psychiatry, Vanderbilt University, Nashville, Tennessee; and Elisabeth.dykens@vanderbilt.edu.
Marisa H FisherVanderbilt Kennedy Center for Research on Human Development and University Center of Excellence on Developmental Disabilities.
Julie Lounds TaylorVanderbilt Kennedy Center for Research on Human Development and University Center of Excellence on Developmental Disabilities,Pediatrics, and.
Warren LambertVanderbilt Kennedy Center for Research on Human Development and University Center of Excellence on Developmental Disabilities.
Nancy MiodragDepartment of Child and Adolescent Development, California State University Northridge, Northridge, California.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
THREE-TIERED PREVENTION MODEL TO BETTER SERVE ALL STUDENP30HD015052 · NICHD · VANDERBILT UNIVERSITY · PI DYKENS, ELISABETH MAY · 1985 to 2014
$18.6M
Conventional vs Mindfulness Intervention in Parents of Children With DisabilitiesRC1AT005612 · NCCIH · VANDERBILT UNIVERSITY · PI DYKENS, ELISABETH MAY · 2009 to 2010
$999k
Risk and Resiliency for Youth With Autism During the Transition to AdulthoodK01MH092598 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TAYLOR, JULIE LOUNDS · 2011 to 2014
$569k
NCATS NIH HHS UL1 TR000445NCCIH NIH HHS RC1 AT005612NICHD NIH HHS P30 HD015052NIMH NIH HHS K01 MH092598
6 · The paper itself

Abstract

backgroundCompared with other parents, mothers of children with autism spectrum disorder or other neurodevelopmental disabilities experience more stress, illness, and psychiatric problems. Although the cumulative stress and disease burden of these mothers is exceptionally high, and associated with poorer outcomes in children, policies and practices primarily serve the identified child with disabilities.

methodsA total of 243 mothers of children with disabilities were consented and randomized into either Mindfulness-Based Stress Reduction (mindfulness practice) or Positive Adult Development (positive psychology practice). Well-trained, supervised peer mentors led 6 weeks of group treatments in 1.5-hour weekly sessions, assessing mothers 6 times before, during, and up to 6 months after treatment. Mothers had children with autism (65%) or other disabilities (35%). At baseline, 85% of this community sample had significantly elevated stress, 48% were clinically depressed, and 41% had anxiety disorders.

resultsUsing slopes-as-outcomes, mixed random effects models, both treatments led to significant reductions in stress, depression, and anxiety, and improved sleep and life satisfaction, with large effects in depression and anxiety. Mothers in Mindfulness-Based Stress Reduction versus Positive Adult Development had greater improvements in anxiety, depression, sleep, and well-being. Mothers of children with autism spectrum disorder improved less in anxiety, but did not otherwise differ from their counterparts.

conclusionsFuture studies are warranted on how trained mentors and professionals can address the unmet mental health needs of mothers of children with developmental disabilities. Doing so improves maternal well-being and furthers their long-term caregiving of children with complex developmental, physical, and behavioral needs.

Indexed as

Children with DisabilitiesFamily HealthMindfulnessAdolescentAdultAsperger SyndromeCaregiversChildChild Development Disorders, PervasiveChild, PreschoolFemaleHumansMaleMiddle AgedMothersParentingautism spectrum disordersdevelopmental disabilitiesmaternal stress and mental healthmindfulness based stress reductionpositive psychology

Identifiers

PMID25049350
PMCPMC4187227

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.