Evidence map›Paper›PMID 25049338›Full record

Trial reportPediatrics2014

Prevention of traumatic stress in mothers of preterms: 6-month outcomes.

Richard J Shaw, Nick St John, Emily Lilo, Booil Jo, William Benitz, David K Stevenson, Sarah M Horwitz

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01307293 (Randomized Controlled Trial of a Brief Cognitive Behavioral Intervention Designed to Prevent and Reduce Symptoms of Posttraumatic Stress in Mothers of Preterm Infants.), which is not on this map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
11.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01307293 nacompletednot on this map

Randomized Controlled Trial of a Brief Cognitive Behavioral Intervention Designed to Prevent and Reduce Symptoms of Posttraumatic Stress in Mothers of Preterm Infants.

TypeinterventionalSponsorStanford UniversityRan2011 to 2014Enrolled110ConditionsStress Disorders, Post-TraumaticArmsCognitive behavior therapy
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  5. Reducing parental trauma and stress in neonatal intensive care: systematic review and meta-analysis of hospital interventions.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Pooled it
  6. Pooled it
  7. Trial
  8. Well-being in parents of infants with neurological conditions: from birth to 6 months after discharge.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  9. A Compassion-Focused Approach to Support Parents After Preterm Birth.Clinical child and family psychology review · 2025
    Review
  10. From NICU to home: meeting the mental health needs of families after discharge.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Richard J ShawDepartment of Psychiatry and Behavioral Sciences, rjshaw@stanford.edu.
Nick St JohnDivision of Neonatology, Stanford University School of Medicine, Palo Alto, California;
Emily LiloDepartment of Pediatrics, University of New Mexico, Albuquerque, New Mexico; and.
Booil JoDepartment of Psychiatry and Behavioral Sciences.
William BenitzDivision of Neonatology, Stanford University School of Medicine, Palo Alto, California;
David K StevensonDivision of Neonatology, Stanford University School of Medicine, Palo Alto, California;
Sarah M HorwitzDepartment of Child and Adolescent Psychiatry, New York University Medical School, New York, New York.
Stanford University · USInstitute of Behavioral Sciences · JPNew York University · USUniversity of New Mexico · US

Funding

Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1RR025744 · NCRR · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2008 to 2011
$22.4M
Research Methods CoreP30MH090322 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOAGWOOD, KIMBERLY E. · 2011 to 2015
$8.1M
Prevention of Postpartum Traumatic Stress in Mothers with Preterm InfantsR34MH086579 · NIMH · STANFORD UNIVERSITY · PI HORWITZ, SARAH MCCUE, SHAW, RICHARD JOHN · 2011 to 2013
$705k
NCRR NIH HHS UL1 RR025744NIMH NIH HHS P30 MH090322NIMH NIH HHS R01-MH086579ANIMH NIH HHS R34 MH086579
6 · The paper itself

Abstract

objectiveSymptoms of posttraumatic stress disorder are a well-recognized phenomenon in mothers of preterm infants, with implications for maternal health and infant outcomes. This randomized controlled trial evaluated 6-month outcomes from a skills-based intervention developed to reduce symptoms of posttraumatic stress disorder, anxiety, and depression.

methodsOne hundred five mothers of preterm infants were randomly assigned to (1) a 6- or 9-session intervention based on principles of trauma-focused cognitive behavior therapy with infant redefinition or (2) a 1-session active comparison intervention based on education about the NICU and parenting of the premature infant. Outcome measures included the Davidson Trauma Scale, the Beck Depression Inventory II, and the Beck Anxiety Inventory. Participants were assessed at baseline, 4 to 5 weeks after birth, and 6 months after the birth of the infant.

resultsAt the 6-month assessment, the differences between the intervention and comparison condition were all significant and sizable and became more pronounced when compared with the 4- to 5-week outcomes: Davidson Trauma Scale (Cohen's d = -0.74, P < .001), Beck Anxiety Inventory (Cohen's d = -0.627, P = .001), Beck Depression Inventory II (Cohen's d = -0.638, P = .002). However, there were no differences in the effect sizes between the 6- and 9-session interventions.

conclusionsA brief 6-session intervention based on principles of trauma-focused cognitive behavior therapy was effective at reducing symptoms of trauma, anxiety, and depression in mothers of preterm infants. Mothers showed increased benefits at the 6-month follow-up, suggesting that they continue to make use of techniques acquired during the intervention phase.

Indexed as

AnxietyCognitive Behavioral TherapyDepressionFemaleHumansInfant, PrematureMothersStress, PsychologicalTreatment Outcomeinterventionneonatal ICUneonatal intensive careposttraumatic stress disorderpremature infantspreterm infantsPTSD

Identifiers

PMID25049338
PMCPMC4187238
OpenAlexW2167536151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.