ArticleYonsei medical journal2014
Architectural changes of the gastrocnemius muscle after botulinum toxin type A injection in children with cerebral palsy.
Article in Yonsei medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Botulinum Neurotoxin A-Induced Muscle Morphology Changes in Children with Cerebral Palsy: A One-Year Follow-Up Study.Toxins · 2025Article
- The state of the art in therapeutic administration of botulinum toxin in children with cerebral palsy: an integrative review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024Review
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- Review
- Article
- Article
- Gait training using a hybrid assistive limb after botulinum toxin treatment for cerebral palsy: a case report.Journal of physical therapy science · 2021Article
- Article
- Rectus Femoris Characteristics in Post Stroke Spasticity: Clinical Implications from Ultrasonographic Evaluation.Toxins · 2020Observational
- Review
- Impact of Altered Gastrocnemius Morphometrics and Fascicle Behavior on Walking Patterns in Children With Spastic Cerebral Palsy.Frontiers in physiology · 2020Article
- Joint and Muscle Assessments of the Separate Effects of Botulinum NeuroToxin-A and Lower-Leg Casting in Children With Cerebral Palsy.Frontiers in neurology · 2020Article
- Comment on: "Botulinum Toxin in the Management of Children with Cerebral Palsy".Paediatric drugs · 2019Article
- Architecture of the Triceps Surae Muscles Complex in Patients with Spastic Hemiplegia: Implication for the Limited Utility of the Silfverskiöld Test.Journal of clinical medicine · 2019Article
- Article
- Comprehensive evaluation of gait, spasticity, and muscle morphology: A case report of a child with spastic paresis treated with Botulinum NeuroToxin-A, serial casting, and physiotherapy.Clinical case reports · 2019Article
- Architectural Changes in the Medial Gastrocnemius on Sonography after Nerve Ablation in Healthy Adults.Yonsei medical journal · 2019Article
- AbobotulinumtoxinA: A Review in Pediatric Lower Limb Spasticity.Paediatric drugs · 2017Review
- Botulinum Toxin Type A Injection for Spastic Equinovarus Foot in Children with Spastic Cerebral Palsy: Effects on Gait and Foot Pressure Distribution.Yonsei medical journal · 2016Article
- Effects of ankle-foot braces on medial gastrocnemius morphometrics and gait in children with cerebral palsy.Journal of children's orthopaedics · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study used ultrasonography (US) to investigate the architectural changes in gastrocnemius muscles (GCM) after botulinum toxin injection (BoNT-A) in children with cerebral palsy (CP). MATERIALS AND
methodsThirteen children with CP who received a BoNT-A injection into their GCM to treat equinus were recruited (9 males and 4 females). Architectural changes in both the medial and lateral heads of the GCM from a total of 20 legs were assessed using B-mode, real-time US. Muscle thickness (MT), fascicle length (FL), and fascicle angle (FA) were measured over the middle of the muscle belly in both a resting and neutral ankle position. Measures at 1 and 3 months after the injection were compared with baseline data taken before the injection.
resultsThe mean age of the subjects was 5.8 (±1.6) years. Spasticity was significantly reduced when measured by both the modified Tardieu scale and the modified Ashworth scale at 1 and 3 months after injection (p<0.05). The MT and FA of both the medial and lateral heads of the GCM were significantly reduced for both neutral and resting ankle positions at 1 and 3 months after the injection. The FL of both the medial and lateral heads of the GCM were significantly increased in a resting position (p<0.05), but not in a neutral position.
conclusionOur results demonstrated muscle architectural changes induced by BoNT-A injection. The functional significances of these changes were discussed.
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