Evidence map›Paper›PMID 25047981›Full record

SynthesisInternational archives of occupational and environmental health2015

Risk of ischemic heart disease following occupational exposure to welding fumes: a systematic review with meta-analysis.

Emina Mocevic, Pernille Kristiansen, Jens Peter Bonde

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International archives of occupational and environmental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Welding Fumes, a Risk Factor for Lung Diseases.International journal of environmental research and public health · 2020
    Pooled it
  2. Occupational exposure to dust and fumes increases risk for future adverse clinical outcomes.American journal of respiratory and critical care medicine · 2026
    Observational
  3. Occupational particle exposure and diabetes: a cohort study in Swedish construction workers.International archives of occupational and environmental health · 2026
    Article
  4. Article
  5. Article
  6. Longitudinal changes in cardiovascular disease-related proteins in welders.International archives of occupational and environmental health · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. An occupational exposure limit for welding fumes is urgently needed.Scandinavian journal of work, environment & health · 2022
    Article
  12. Article
  13. A study of atherothrombotic biomarkers in welders.International archives of occupational and environmental health · 2019
    Article
  14. [Workers especially sensitive to cardiovascular risk].Revista espanola de salud publica · 2019
    Article
  15. Occupational exposure to particles and mitochondrial DNA - relevance for blood pressure.Environmental health : a global access science source · 2017
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emina MocevicDepartment of Occupational and Environmental Medicine, Bispebjerg University Hospital, Bispebjerg Bakke 23, Opgang 33, 2400, Copenhagen NV, Denmark, emina.mocevic.01@regionh.dk.
Pernille Kristiansen
Jens Peter Bonde

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAir pollution has been linked to an increased risk of ischemic heart disease (IHD), but less is known about occupational exposure to welding fumes and the risk of IHD. The objective of this paper was to review the epidemiological evidence on causal links between welding fume exposure and risk of IHD and to investigate whether the risk of IHD depends on specific welding characteristics.

methodsA systematic search in Medline 1979-2013 and EMBASE 1974-2013 identified 18 epidemiological studies with at least one risk estimate of IHD morbidity or mortality among workers exposed to welding fumes. Following an assessment of completeness of reporting, confounding, and bias, each risk estimate was characterized as more or less reliable. Pooled risk estimates were computed across studies by random effect meta-analyses.

resultsThe weighted relative risk (RR) for IHD following exposure to welding fumes was 1.09 [95 % confidence interval (CI) 1.00, 1.19]. We calculated a RR of 1.39 (95 % CI 0.96, 2.02) among studies using an internal reference group and 1.08 (95 % CI 0.99, 1.18) for studies using an external reference group. An increased risk was observed for acute myocardial infarction RR = 1.69 (95 % CI 1.18, 2.42) and other IHDs RR = 1.06 (95 % CI 0.98, 1.14). There was too limited evidence to evaluate the risk of IHD related to specific welding characteristics.

conclusionSeveral studies indicate that welding is associated with a moderately increased risk of IHD; however, bias and confounding cannot be ruled out with reasonable confidence.

Indexed as

WeldingAir Pollutants, OccupationalCohort StudiesHumansInhalation ExposureMyocardial IschemiaOccupational ExposureRisk FactorsAir Pollutants, Occupational

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.