ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2014
Historical roots of centrosome research: discovery of Boveri's microscope slides in Würzburg.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 70 citations in OpenAlex.
- Advances in high-resolution imaging of centrioles and cilia.Journal of cell science · 2025Review
- ZO-2 is a scaffold at the centriole and mitotic spindle poles that enhances microtubule stability and supports the proper development of mitotic spindles and cilia.Cell and tissue research · 2025Article
- When DNA Mutations Interplay with Cellular Proliferation: A Narrative History of Theories of Carcinogenesis.Cancers · 2024Review
- Positioning centrioles and centrosomes.The Journal of cell biology · 2024Review
- Emerging roles of centrosome cohesion.Open biology · 2022Review
- Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights.Blood science (Baltimore, Md.) · 2022Review
- The Centriole's Role in Miscarriages.Frontiers in cell and developmental biology · 2022Article
- Structural and Functional Insights into the Microtubule Organizing Centers ofMicroorganisms · 2021Review
- Centrosome instability: when good centrosomes go bad.Cellular and molecular life sciences : CMLS · 2021Review
- Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies.Cancer metastasis reviews · 2021Review
- Centrosome dysfunction: a link between senescence and tumor immunity.Signal transduction and targeted therapy · 2020Review
- Review
- Choreography of the centrosome.Heliyon · 2020Review
- Cellular and molecular aspects of oocyte maturation and fertilization: a perspective from the actin cytoskeleton.Zoological letters · 2020Review
- Review
- Harnessing biomolecular condensates in living cells.Journal of biochemistry · 2019Review
- Review
- Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse.Scientific reports · 2018Article
- Review
- Centrosome Remodelling in Evolution.Cells · 2018Review
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1 author at 1 institution in 1 country.
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Abstract
Boveri's visionary monograph 'Ueber die Natur der Centrosomen' (On the nature of centrosomes) in 1900 was founded primarily on microscopic observations of cleaving eggs of sea urchins and the roundworm parasite Ascaris. As Boveri wrote in the introductory paragraph, his interests were less about morphological aspects of centrosomes, but rather aimed at an understanding of their physiological role during cell division. The remarkable transition from observations of tiny dot-like structures in fixed and sectioned material to a unified theory of centrosome function (which in essence still holds true today) cannot be fully appreciated without examining Boveri's starting material, the histological specimens. It was generally assumed that the microscope slides were lost during the bombing of the Zoological Institute in Würzburg at the end of WWII. Here, I describe the discovery of a number of Boveri's original microscope slides with serial sections of early sea urchin and Ascaris embryos, stained by Heidenhain's iron haematoxylin method. Some slides bear handwritten notes and sketches by Boveri. Evidence is presented that the newly discovered slides are part of the original material used by Boveri for his seminal centrosome monograph.
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