ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2014
When fate follows age: unequal centrosomes in asymmetric cell division.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Article
- Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells.Biochemical Society transactions · 2020Review
- Dynamic centriolar localization of Polo and Centrobin in early mitosis primes centrosome asymmetry.PLoS biology · 2020Article
- Centrioles and Ciliary Structures during Male Gametogenesis in Hexapoda: Discovery of New Models.Cells · 2020Review
- NANOG/NANOGP8 Localizes at the Centrosome and is Spatiotemporally Associated with Centriole Maturation.Cells · 2020Article
- The Singularity of the Drosophila Male Germ Cell Centriole: The Asymmetric Distribution of Sas4 and Sas6.Cells · 2020Article
- Review
- Cell polarity: having and making sense of direction-on the evolutionary significance of the primary cilium/centrosome organ in Metazoa.Open biology · 2018Review
- Nanocomposites Based on Biodegradable Polymers.Materials (Basel, Switzerland) · 2018Review
- Breaking Symmetry - Asymmetric Histone Inheritance in Stem Cells.Trends in cell biology · 2017Review
- Shh-mediated centrosomal recruitment of PKA promotes symmetric proliferative neuroepithelial cell division.Nature cell biology · 2017Article
- Distinct mechanisms eliminate mother and daughter centrioles in meiosis of starfish oocytes.The Journal of cell biology · 2016Article
- Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP.eLife · 2015Article
- Centrosomes back in the limelight.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Article
- Exploring the evolutionary history of centrosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A strong correlation between centrosome age and fate has been reported in some stem cells and progenitors that divide asymmetrically. In some cases, such stereotyped centrosome behaviour is essential to endow stemness to only one of the two daughters, whereas in other cases causality is still uncertain. Here, we present the different cell types in which correlated centrosome age and fate has been documented, review current knowledge on the underlying molecular mechanisms and discuss possible functional implications of this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.