Evidence map›Paper›PMID 25047617›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2014

Communication, the centrosome and the immunological synapse.

Jane C Stinchcombe, Gillian M Griffiths

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025
    Article
  3. Regulation of INPP5E in Ciliogenesis, Development, and Disease.International journal of biological sciences · 2025
    Review
  4. Article
  5. Article
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  8. Article
  9. Article
  10. Review
  11. Article
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  14. Article
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  16. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jane C StinchcombeCambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 OXY, UK.
Gillian M GriffithsCambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 OXY, UK gg305@cam.ac.uk.

Funding

Wellcome Trust 100140Wellcome Trust 103930
6 · The paper itself

Abstract

Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show parallels to centrosome (basal body) polarization seen in cilia and flagella, and the cellular communication that is now known to occur at all of these sites.

Indexed as

Biological EvolutionModels, ImmunologicalAnimalsCell CommunicationCell PolarityCentrosomeCiliaImmune SystemImmunological Synapsescentrosomeciliaimmunological synapsekilling

Identifiers

PMID25047617
PMCPMC4113107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.