SynthesisPloS one2014
Tai Chi for improvement of motor function, balance and gait in Parkinson's disease: a systematic review and meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 10 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- The effects of exercise dose on patients with Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.Journal of neurology · 2023Pooled it
- Physical exercise and its effects on people with Parkinson's disease: Umbrella review.PloS one · 2023Pooled it
- Pooled it
- Efficacy of Traditional Chinese Exercise in Improving Gait and Balance in Cases of Parkinson's Disease: A Systematic Review and Meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Mind-Body Therapies From Traditional Chinese Medicine: Evidence Map.Frontiers in public health · 2021Pooled it
- Physiotherapy in Parkinson's Disease: A Meta-Analysis of Present Treatment Modalities.Neurorehabilitation and neural repair · 2020Pooled it
- The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson's disease: A systematic review and meta-analysis.Parkinsonism & related disorders · 2017Pooled it
- Health benefits of tai chi: What is the evidence?Canadian family physician Medecin de famille canadien · 2016Pooled it
- The efficacy of traditional Chinese Medical Exercise for Parkinson's disease: a systematic review and meta-analysis.PloS one · 2015Pooled it
- Effect of Pro-kin visual feedback balance training on balance function of individuals with early Parkinson's disease: a randomized controlled pilot trial.African health sciences · 2023Trial
- Effects of a Tai Chi-Based Stroke Rehabilitation Program on Symptom Clusters, Physical and Cognitive Functions, and Quality of Life: A Randomized Feasibility Study.International journal of environmental research and public health · 2021Trial
- A Cluster Randomized Trial of Tai Chi vs Health Education in Subsidized Housing: The MI-WiSH Study.Journal of the American Geriatrics Society · 2019Trial
- The effectiveness of Tai Chi for patients with Parkinson's disease: study protocol for a randomized controlled trial.Trials · 2015Trial
- Evidence map of Tai Chi interventions for older adults.Frontiers in public health · 2026Review
- Tai Chi exercise and neuroplasticity: a narrative review according to neural mechanisms and clinical utilizations in brain health.Frontiers in neuroscience · 2026Review
- Effect of traditional Chinese exercises on motor function, balance, gait, and quality of life in patients with Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurology · 2025Review
- Harnessing Mirror Neurons: A New Frontier in Parkinson's Disease Rehabilitation-A Scoping Review of the Literature.Journal of clinical medicine · 2024Article
- Quantifying Changes in Dexterity as a Result of Piano Training in People with Parkinson's Disease.Sensors (Basel, Switzerland) · 2024Article
- Central mechanisms of muscle tone regulation: implications for pain and performance.Frontiers in neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, several studies assessed the effectiveness of Tai Chi for Parkinson's disease (PD), but the role of Tai Chi in the management of PD remained controversial. Therefore, the purpose of this systematic review is to evaluate the evidence on the efficacy of Tai Chi for PD.
methodsSix English and Chinese electronic databases, up to April 2014, were searched to identify relevant studies. The risk of bias in eligible studies was assessed by Cochrane Collaboration's tools. The primary outcomes were motor function, balance and gait in individuals with PD. Standardized mean difference (SMD) and 95% confidence intervals (CI) of random-effect model were calculated. And heterogeneity was assessed based on the I2 statistic.
results7 randomized controlled trials and 1 non-randomized controlled trial were eligible. The aggregated results suggested that Tai Chi showed beneficial effects in improving motor function (SMD, -0.57; 95% CI -1.11 to -0.04; p = 0.03), balance (SMD, 1.22; 95% CI 0.80 to 1.65; p<0.00001) and functional mobility (SMD, 1.06; 95% CI 0.68 to 1.44; p<0.00001) in patients with PD, but not in improving gait velocity (SMD, -0.02; 95% CI -0.58 to 0.54; p = 0.94), step length (SMD, -0.00; 95% CI -0.57 to 0.56; p = 0.99), or gait endurance (SMD, 0.53; 95% CI -0.07 to 1.12; p = 0.08). Comparing with other active therapies, however, Tai Chi only showed better effects in improving balance (SMD, 0.74; 95% CI 0.38 to 1.10; p<0.0001).
conclusionTai Chi should be a valid complementary and alternative therapy for PD, especially in improving motor function and balance. However, more studies with long follow-up are warrant to confirm the current finding of Tai Chi for PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.