Evidence map›Paper›PMID 25046699›Full record

ArticleMagnetic resonance in medicine2015

A 31-channel MR brain array coil compatible with positron emission tomography.

Christin Y Sander, Boris Keil, Daniel B Chonde, Bruce R Rosen, Ciprian Catana, Lawrence L Wald

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
    Review
  2. Article
  3. Review
  4. [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  5. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
  6. PET/MRI of atherosclerosis.Cardiovascular diagnosis and therapy · 2020
    Review
  7. Microstrip Transmission Line RF Coil for a PET/MRI Insert.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020
    Article
  8. Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
  9. Article
  10. Article
  11. Effects of flow changes on radiotracer binding: Simultaneous measurement of neuroreceptor binding and cerebral blood flow modulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  12. Article
  13. Review
  14. Article
  15. Applications of PET-MRI in musculoskeletal disease.Journal of magnetic resonance imaging : JMRI · 2018
    Review
  16. Review
  17. In Vivo [ACS chemical neuroscience · 2018
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christin Y SanderAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Boris KeilAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Daniel B ChondeAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Bruce R RosenAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Ciprian CatanaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Lawrence L WaldAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

Funding

ULTRAHIGH FIELD TECHNOLOGY FOR FUNCTIONAL IMAGINGP41RR014075 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI WALD, LAWRENCE L · 1999 to 2011
$16.4M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Advanced Multimodal Neuroimaging Training GrantR90DA023427 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2006 to 2015
$2.8M
MR-assisted PET data optimization for neuroimaging studiesR01EB014894 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI CATANA, CIPRIAN · 2013 to 2016
$2.6M
Combined MRI/PET Imager for Simultaneous Acquisition of PET/MRI DataS10RR022976 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI JENKINS, BRUCE · 2007 to 2007
$2.0M
PET CAMERA FOR BRAIN IMAGING: SCHIZOPHRENIA, BIPOLAR DISORDERS10RR019933 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$500k
NCRR NIH HHS P41 RR014075NCRR NIH HHS S10 RR019933NCRR NIH HHS S10 RR022976NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41EB015896NIBIB NIH HHS R01 EB014894NIDA NIH HHS R90 DA023427NIDA NIH HHS R90DA023427
6 · The paper itself

Abstract

purposeSimultaneous acquisition of MR and positron emission tomography (PET) images requires the placement of the MR detection coil inside the PET detector ring where it absorbs and scatters photons. This constraint is the principal barrier to achieving optimum sensitivity on each modality. Here, we present a 31-channel PET-compatible brain array coil with reduced attenuation but improved MR sensitivity.

methodsA series of component tests were performed to identify tradeoffs between PET and MR performance. Aspects studied include the remote positioning of preamplifiers, coax size, coil trace size/material, and plastic housing. We then maximized PET performance at minimal cost to MR sensitivity. The coil was evaluated for MR performance (signal to noise ratio [SNR], g-factor) and PET attenuation.

resultsThe coil design showed an improvement in attenuation by 190% (average) compared with conventional 32-channel arrays, and no loss in MR SNR. Moreover, the 31-channel coil displayed an SNR improvement of 230% (cortical region of interest) compared with a PET-optimized 8-channel array with similar attenuation properties. Implementing attenuation correction of the 31-channel array successfully removed PET artifacts, which were comparable to those of the 8-channel array.

conclusionThe design of the 31-channel PET-compatible coil enables higher sensitivity for PET/MR imaging, paving the way for novel applications in this hybrid-imaging domain.

Indexed as

Brain MappingEquipment DesignHumansMagnetic Resonance ImagingMultimodal ImagingPositron-Emission TomographySensitivity and Specificityintegrated PET/MRmultichannel brain arrayPET-optimized coilRF coil attenuationsimultaneous PET/MR

Identifiers

PMID25046699
PMCPMC4500638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.