Evidence map›Paper›PMID 25046661›Full record

ArticleJournal of visualized experiments : JoVE2014

Voluntary breath-hold technique for reducing heart dose in left breast radiotherapy.

Frederick R Bartlett, Ruth M Colgan, Ellen M Donovan, Karen Carr, Steven Landeg, Nicola Clements, Helen A McNair, Imogen Locke, Philip M Evans, Joanne S Haviland and 2 more

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Review
  3. Dosimetric advantage of ipsilateral lung and cardiac sparing of left breast cancer prone position compared with supine free breathing in the COVID-19 era and personalized medicine.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
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  7. Review
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  19. Voluntary breath-hold reduces dose to organs at risk in radiotherapy of left-sided breast cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Frederick R BartlettDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust; frederick.bartlett@rmh.nhs.uk.
Ruth M ColganDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Ellen M DonovanDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Karen CarrDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Steven LandegDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Nicola ClementsDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Helen A McNairDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Imogen LockeDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.
Philip M EvansCentre for Vision, Speech and Signal Processing, Faculty of Engineering and Physical Sciences, University of Surrey.
Joanne S HavilandClinical Trials and Statistics Unit (ICR-CTSU), Institute of Cancer Research, Sutton, UK.
John R YarnoldDivision of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, UK.
Anna M KirbyDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust.

Funding

Cancer Research UK 10588Department of Health PB-PG-1010-23003Medical Research Council G9600656
6 · The paper itself

Abstract

Breath-holding techniques reduce the amount of radiation received by cardiac structures during tangential-field left breast radiotherapy. With these techniques, patients hold their breath while radiotherapy is delivered, pushing the heart down and away from the radiotherapy field. Despite clear dosimetric benefits, these techniques are not yet in widespread use. One reason for this is that commercially available solutions require specialist equipment, necessitating not only significant capital investment, but often also incurring ongoing costs such as a need for daily disposable mouthpieces. The voluntary breath-hold technique described here does not require any additional specialist equipment. All breath-holding techniques require a surrogate to monitor breath-hold consistency and whether breath-hold is maintained. Voluntary breath-hold uses the distance moved by the anterior and lateral reference marks (tattoos) away from the treatment room lasers in breath-hold to monitor consistency at CT-planning and treatment setup. Light fields are then used to monitor breath-hold consistency prior to and during radiotherapy delivery.

Indexed as

Breath HoldingBreast NeoplasmsFemaleHeartHeart DiseasesHumansRadiation InjuriesRadiotherapyRadiotherapy Planning, Computer-AssistedRandomized Controlled Trials as Topic

Identifiers

PMID25046661
PMCPMC4211647

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.