Evidence map›Paper›PMID 25046426›Full record

ArticleACS combinatorial science2014

High-throughput analysis of molecular orientation on surfaces by NEXAFS imaging of curved sample arrays.

Joe E Baio, Cherno Jaye, Daniel A Fischer, Tobias Weidner

Abstract read
In one paragraph

Article in ACS combinatorial science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Evidence of a molecular boundary lubricant at snakeskin surfaces.Journal of the Royal Society, Interface · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joe E BaioMax Planck Institute for Polymer Research , 55128 Mainz, Germany.
Cherno Jaye
Daniel A Fischer
Tobias Weidner

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G, GAMBLE, LARA · 2003 to 2019
$17.6M
NIBIB NIH HHS P41 EB002027
6 · The paper itself

Abstract

Near-edge X-ray absorption fine structure (NEXAFS) spectroscopy provides detailed information about the orientation and alignment of thin films. NEXAFS is a synchrotron-based technique-the availability of beam-time per user is typically limited to no more than a few weeks per year. The limited availability is currently a true barrier for using NEXAFS in combinatorial studies of molecular alignment. We have recently demonstrated how large area full field NEXAFS imaging allows users to pursue combinatorial studies of surface chemistry. Now we report an extension of this approach which allows the acquisition of orientation information from a single NEXAFS image. An array with 80 elements (samples), containing eight series of different surface modifications, was mounted on a curved substrate allowing the collection of NEXAFS spectra with a range of orientations with respect to the X-ray beam. Images collected from this array show how hyperspectral NEXAFS data collected from curved surfaces can be used for high-throughput molecular orientation analysis.

Indexed as

High-Throughput Screening AssaysPolymersProteinsSiliconSurface-Active AgentsSurface PropertiesX-Ray Absorption SpectroscopyPolymersProteinsSiliconSurface-Active Agentsalkanethiolangle-resolved photoemissioncombinatorial scienceimaging NEXAFSmolecular orderself-assembled monolayers

Identifiers

PMID25046426
PMCPMC4608249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.