Evidence map›Paper›PMID 25046050›Full record

ArticleBioanalysis2014

Development of miniature mass spectrometry systems for bioanalysis outside the conventional laboratories.

Xiaoyu Zhou, Jiangjiang Liu, Robert Graham Cooks, Zheng Ouyang

Open access · greenAbstract read
In one paragraph

Article in Bioanalysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Quantitative mass spectrometry methods for pharmaceutical analysis.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaoyu ZhouWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Jiangjiang Liu
Robert Graham Cooks
Zheng Ouyang
Purdue University West Lafayette · US

Funding

Development of a Point-of-Care Mass Spectrometry Analysis SystemR01GM106016 · NIGMS · PURDUE UNIVERSITY · PI OUYANG, ZHENG · 2013 to 2016
$1.1M
Desorption Electrospray Ionization Mass Spectrometry Imaging in Clinical DiagnostR21EB015722 · NIBIB · PURDUE UNIVERSITY · PI COOKS, ROBERT GRAHAM · 2013 to 2014
$388k
Tissue Imaging Using Desorption Electrospray Ionization Mass SpectrometryR21EB009459 · NIBIB · PURDUE UNIVERSITY · PI COOKS, ROBERT GRAHAM · 2009 to 2010
$384k
Paper Spray Ionization Mass Spectrometry Device for Direct Analysis of Biofluid SR21RR031246 · NCRR · PURDUE UNIVERSITY · PI OUYANG, ZHENG · 2010 to 2011
$358k
Paper Spray Ionization Mass Spectrometry Device for Direct Analysis of Biofluid SR21GM103454 · NIGMS · PURDUE UNIVERSITY · PI OUYANG, ZHENG · 2012 to 2012
$178k
NCRR NIH HHS R21 RR031246NIBIB NIH HHS 1R21EB009459NIBIB NIH HHS 1R21EB015722NIBIB NIH HHS R21 EB009459NIBIB NIH HHS R21 EB015722NIGMS NIH HHS 1R01GM106016-01NIGMS NIH HHS 8R21GM103454NIGMS NIH HHS R01 GM106016NIGMS NIH HHS R21 GM103454
6 · The paper itself

Abstract

Mass spectrometry (MS) is known for highly specific and sensitive analysis. The general applicability of this technique makes it a good candidate for biological applications over a much broader range than is now the case. The limiting factors preventing MS from being applied at the biologist's bench or in a physician's office are identified as the large size of the systems, as well as the complicated analytical procedures required. An approach for developing miniature MS analysis systems with simplified operational procedures is described and the associated technical developments are discussed.

Indexed as

Chromatography, High Pressure LiquidHumansLaboratoriesMass SpectrometryTandem Mass Spectrometry

Identifiers

PMID25046050
PMCPMC4139974
OpenAlexW2016010199

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.