Evidence map›Paper›PMID 25045721›Full record

ArticleTechnology2014

Rapid ratiometric biomarker detection with topically applied SERS nanoparticles.

Yu Winston Wang, Altaz Khan, Madhura Som, Danni Wang, Ye Chen, Steven Y Leigh, Daphne Meza, Patrick Z McVeigh, Brian C Wilson, Jonathan T C Liu

Abstract read
In one paragraph

Article in Technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Multiplexed Raman Imaging in Tissues and Living Organisms.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Effect of staining temperature on topical dual stain imaging of tissue specimens for tumor identification.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Theranostics · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yu Winston Wang
Altaz Khan
Madhura Som
Danni Wang
Ye Chen
Steven Y Leigh
Daphne Meza
Patrick Z McVeigh
Brian C Wilson
Jonathan T C Liu
Stony Brook University · USPrincess Margaret Cancer Centre · CAUniversity of Toronto · CA

Funding

Endoscopic molecular imaging of esophageal cancer with multiplexed Raman nanopartR21EB015016 · NIBIB · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C. · 2013 to 2014
$493k
NIBIB NIH HHS R21 EB015016
6 · The paper itself

Abstract

Multiplexed surface-enhanced Raman scattering (SERS) nanoparticles (NPs) offer the potential for rapid molecular phenotyping of tissues, thereby enabling accurate disease detection as well as patient stratification to guide personalized therapies or to monitor treatment outcomes. The clinical success of molecular diagnostics based on SERS NPs would be facilitated by the ability to accurately identify tissue biomarkers under time-constrained staining and detection conditions with a portable device.

Identifiers

PMID25045721
PMCPMC4103661
OpenAlexW2030180978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.