Evidence map›Paper›PMID 25045683›Full record

ArticleBioMed research international2014

Denture-related stomatitis is associated with endothelial dysfunction.

Joanna Maciąg, Grzegorz Osmenda, Daniel Nowakowski, Grzegorz Wilk, Anna Maciąg, Tomasz Mikołajczyk, Ryszard Nosalski, Agnieszka Sagan, Magdalena Filip, Mirosław Dróżdż and 3 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Host's Immunity andMicroorganisms · 2022
    Review
  5. Article
  6. International journal of dentistry · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Joanna MaciągDepartment of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland.ORCID 0000-0002-9759-011X
Grzegorz OsmendaDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.
Daniel NowakowskiDepartment of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland.
Grzegorz WilkDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.
Anna MaciągZbigniew Żak Voivodeship Dental Clinic, Cracow, Poland.
Tomasz MikołajczykDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.
Ryszard NosalskiDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.ORCID 0000-0003-4661-8773
Agnieszka SaganDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.
Magdalena FilipDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.
Mirosław DróżdżDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland.
Jolanta LosterDepartment of Dental Prosthetics, Institute of Dentistry at Jagiellonian University Medical Collage, Cracow, Poland.ORCID 0000-0002-8759-0810
Tomasz J GuzikDepartment of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.
Marta Cześnikiewicz-GuzikDepartment of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.ORCID 0000-0002-7444-1373
Jagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledOral inflammation, such as periodontitis, can lead to endothelial dysfunction, accelerated atherosclerosis, and vascular dysfunction. The relationship between vascular dysfunction and other common forms of oral infections such as denture-related stomatitis (DRS) is unknown. Similar risk factors predispose to both conditions including smoking, diabetes, age, and obesity. Accordingly, we aimed to investigate endothelial function and major vascular disease risk factors in 44 consecutive patients with dentures with clinical and microbiological features of DRS (n = 20) and without DRS (n = 24). While there was a tendency for higher occurrence of diabetes and smoking, groups did not differ significantly in respect to major vascular disease risk factors. Groups did not differ in main ambulatory blood pressure, total cholesterol, or even CRP. Importantly, flow mediated dilatation (FMD) was significantly lower in DRS than in non-DRS subjects, while nitroglycerin induced vasorelaxation (NMD) or intima-media thickness (IMT) was similar. Interestingly, while triglyceride levels were normal in both groups, they were higher in DRS subjects, although they did not correlate with either FMD or NMD.

conclusionsDenture related stomatitis is associated with endothelial dysfunction in elderly patients with dentures. This is in part related to the fact that diabetes and smoking increase risk of both DRS and cardiovascular disease.

Indexed as

AgedAtherosclerosisCardiovascular DiseasesCarotid Intima-Media ThicknessCholesterolDenturesEndothelial CellsFemaleHumansMaleMiddle AgedRisk FactorsSmokingStomatitisCholesterol

Identifiers

PMID25045683
PMCPMC4090512
OpenAlexW2123575168

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.