ArticleThe American journal of case reports2014
Peripheral primitive neuroectodermal tumor of the dura in a 51-year-old woman following intensive treatment for breast cancer.
Article in The American journal of case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Diagnosis, treatment, and postoperative follow-up of intracranial Ewing sarcoma (EWS): a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Primary Intracranial Ewing Sarcoma Arising from the Cavernous Sinus in an Older Woman with a History of Intensive Breast Cancer Treatment: A Case Report.NMC case report journal · 2025Article
- Primary intracranial peripheral primitive neuroectodermal tumor: lessons from an exceptionally rare neoplasm. Illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- The role of miR-223 in breast cancer; an integrated analysis.Molecular biology reports · 2023Article
- Primary Intracranial Ewing Sarcoma WithBrain tumor research and treatment · 2023Article
- Primary intracranial extraosseous Ewing's sarcoma of the skull base in an elderly adult: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Primitive Neuroectodermal Tumour of Subcutaneous Tissue Presenting as a Shoulder Lump: A Case Report.JNMA; journal of the Nepal Medical Association · 2022Article
- Primary intracranial peripheral primitive neuroectodermal tumor in an adult patient with aphasia: A rare case report.Clinical case reports · 2022Article
- Case report: Primary intracranial EWs/PNET in adults: Clinical experience and literature review.Frontiers in oncology · 2022Article
- Primary intracranial Ewing sarcoma/ peripheral primitive neuroectodermal tumor, an entity of unacquaintance: a series of 8 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Primary Intracranial Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Mimicking Meningioma: A Case Report and Literature Review.Frontiers in oncology · 2020Article
- MicroRNA-200b Impacts Breast Cancer Cell Migration and Invasion by Regulating Ezrin-Radixin-Moesin.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Ewing's Sarcoma as a Second Malignancy in Long-Term Survivors of Childhood Hematologic Malignancies.Sarcoma · 2016Article
- Primary intracranial dural-based Ewing sarcoma/peripheral primitive neuroectodermal tumor mimicking a meningioma: A rare tumor with review of literature.Asian journal of neurosurgeryReview
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
patientFemale, 51. FINAL DIAGNOSIS: Ewing sarcoma. SYMPTOMS: Visual disturbances. MEDICATION: -. CLINICAL PROCEDURE: -. SPECIALTY: Oncology.
objectiveRare disease.
backgroundPrimitive neuroectodermal tumor/Ewing sarcoma (PNET/EWS) is a round blue cell sarcoma that shows varying degrees of neuroectodermal differentiation. PNET/EWS as a primary intracranial tumor is extremely uncommon. CASE REPORT: We report a unique case of peripheral PNET presenting as an intracranial mass in an adult following chemotherapy and radiotherapy for a solid tumor. A 51-year-old woman with previously treated left breast cancer was evaluated for a newly developed brain mass. She underwent craniotomy with resection. Surgical pathology was consistent with a peripheral PNET/EWS with Ewing sarcoma gene translocation. She was treated appropriately with vincristine, cyclophosphamide, and doxorubicin (later dactinomycin) alternating with ifosfamide and etoposide.
conclusionsAlthough development of PNET/EWS presenting along the CNS is exceedingly rare in adults, establishing the proper diagnosis of this "small blue cell tumor" is critical. The further distinction between central PNET and peripheral PNET can greatly impact both prognosis and treatment. Our case also highlights the importance of considering the impact of prior intensive therapies, including radiation and chemotherapy, on predisposing to future PNET/EWS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.