Evidence map›Paper›PMID 25045339›Full record

ArticleInternational journal of probiotics & prebiotics2012

DETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES.

F Salami, M Abels, H Hyöty, F Vaziri-Sani, Ca Aronsson, K Vehik, A Delli, Wa Hagopian, M Rewers, Ag Ziegler and 6 more

Abstract read
In one paragraph

Article in International journal of probiotics & prebiotics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

F SalamiDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
M AbelsDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
H HyötyDepartment of Virology, Tampere University Hospital, Tampere, Finland.
F Vaziri-SaniDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
Ca AronssonDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
K VehikMorsani College of Medicine, Pediatrics Epidemiology Center, University of South Florida, Tampa, FL, USA.
A DelliDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
Wa HagopianPacific Northwest Diabetes Research Institute, Seattle, WA, USA.
M RewersBarbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO, USA.
Ag ZieglerDiabetes Research Institute, Technische Universität München, Munich, Germany.
O SimellDepartment of Pediatrics, University of Turku, Turku, Finland.
B AkolkarDDEMD, NIDDK, Bethesda, MD, USA.
J KrischerMorsani College of Medicine, Pediatrics Epidemiology Center, University of South Florida, Tampa, FL, USA.
J SheCenter for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA, USA.
A LernmarkDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.
the TEDDY study group

Funding

The Environmental Triggers of Diabetes (TEDDY) in SwedenU01DK063861 · NIDDK · UNIVERSITY OF WASHINGTON · PI LERNMARK, AKE · 2003 to 2022
$13.4M
The TEDDY Study: Georgia/Florida Clinical CenterU01DK063865 · NIDDK · MEDICAL COLLEGE OF GEORGIA (MCG) · PI MCINDOE, RICHARD A. · 2003 to 2022
$12.3M
The Environmental Determinants of Diabetes in Youth: Washington Clinical CenterU01DK063829 · NIDDK · PACIFIC NORTHWEST RESEARCH INSTITUTE · PI HAGOPIAN, WILLIAM A. · 2003 to 2022
$11.8M
The Environmental Triggers of Diabetes (TEDDY)UC4DK063861 · NIDDK · LUNDS UNIVERSITET · PI LERNMARK, AKE · 2013 to 2013
$5.7M
The TEDDY Study: Georgia/Florida Clinical CenterUC4DK063865 · NIDDK · AUGUSTA UNIVERSITY · PI SHE, JIN-XIONG · 2013 to 2013
$5.3M
The Environmental Determinants of Diabetes in the Young (TEDDY) Colorado ClinicalUC4DK063821 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 2013 to 2013
$4.9M
The Environmental Determinants of Diabetes in Youth: Washington Clinical CenterUC4DK063829 · NIDDK · PACIFIC NORTHWEST RESEARCH INSTITUTE · PI HAGOPIAN, WILLIAM A. · 2013 to 2013
$4.6M
NIDDK NIH HHS HHSN267200700014CNIDDK NIH HHS U01 DK063829NIDDK NIH HHS U01 DK063861NIDDK NIH HHS U01 DK063865NIDDK NIH HHS UC4 DK063821NIDDK NIH HHS UC4 DK063829NIDDK NIH HHS UC4 DK063861NIDDK NIH HHS UC4 DK063865
6 · The paper itself

Abstract

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and inter-individually from <0.5 - 736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mail-in stool samples from infants should prove useful in analyzing probiotics in childhood.

Indexed as

Autoimmune DiabetesCeliac DiseaseInfantsMicrofloraProbiotics

Identifiers

PMID25045339
PMCPMC4101081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.