Observational studyThe Korean journal of internal medicine2014
Ferritin as a predictor of decline in residual renal function in peritoneal dialysis patients.
Observational study in The Korean journal of internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- The Impact of Persistent Iron Overload and Ferritin Trend on the Clinical Outcome of Peritoneal Dialysis Patients: A Retrospective Study Over 10 Years.Kidney medicine · 2026Article
- Serum ferritin is a superior biomarker for evaluating disease activity and kidney injury compared with C-reactive protein in anti-neutrophil cytoplasmic antibody-associated vasculitis.Clinical rheumatology · 2025Article
- On the importance of the interplay of residual renal function with clinical outcomes in end-stage kidney disease.Journal of nephrology · 2022Review
- Association Between Iron Metabolism and Acute Kidney Injury in Critically Ill Patients With Diabetes.Frontiers in endocrinology · 2022Article
- Systemic inflammation modulates the ability of serum ferritin to predict all-cause and cardiovascular mortality in peritoneal dialysis patients.BMC nephrology · 2020Article
- Extracellular volume expansion and the preservation of residual renal function in Korean peritoneal dialysis patients: a long-term follow up study.Clinical and experimental nephrology · 2016Article
- Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.BioMed research international · 2016Observational
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6 authors at 2 institutions in 1 country.
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Abstract
BACKGROUND/
aims
aimsInflammation is an important factor in renal injury. Ferritin, an inflammatory marker, is considered an independent predictor of rapid renal progression in patients with chronic kidney disease. However, the relationship between ferritin and residual renal function (RRF) in patients undergoing peritoneal dialysis (PD) remains unclear.
methodsWe reviewed the medical records of patients who started PD between June 2001 and March 2012 at Soonchunhyang University Bucheon Hospital, Korea. A total of 123 patients were enrolled in the study. At 1 month after the initiation of PD, RRF was determined by a 24-hour urine collection and measured every 6 months thereafter. Clinical and biochemical data at the time of the initial 24-hour urine collection were considered as baseline.
resultsThe RRF reduction rate was significantly greater in patients with high ferritin (ferritin ≥ 250 ng/mL) compared with those with low ferritin (ferritin < 250 ng/mL; -1.71 ± 1.36 mL/min/yr/1.73 m(2) vs. -0.84 ± 1.63 mL/min/yr/1.73 m(2), respectively; p = 0.007). Pearson correlation analysis revealed a significant negative correlation between the baseline serum ferritin level and the RRF reduction rate (r = -0.219, p = 0.015). Using multiple linear regression analysis and adjusting for other risk factors, baseline serum ferritin was an independent factor for the RRF reduction rate (β = -0.002, p = 0.002).
conclusionsIn this study we showed that a higher ferritin level was significantly associated with a more rapid RRF decline in patients undergoing PD.
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