Evidence map›Paper›PMID 25045293›Full record

ArticleThe Korean journal of internal medicine2014

Prediction of infarct severity from triiodothyronine levels in patients with ST-elevation myocardial infarction.

Dong Hun Kim, Dong-Hyun Choi, Hyun-Wook Kim, Seo-Won Choi, Bo-Bae Kim, Joong-Wha Chung, Young-Youp Koh, Kyong-Sig Chang, Soon-Pyo Hong

Open access · goldAbstract read
In one paragraph

Article in The Korean journal of internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dong Hun KimDepartment of Radiology, Chosun University School of Medicine, Gwangju, Korea.
Dong-Hyun ChoiDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Hyun-Wook KimDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Seo-Won ChoiDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Bo-Bae KimDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Joong-Wha ChungDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Young-Youp KohDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Kyong-Sig ChangDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Soon-Pyo HongDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Chosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe aim of the present study was to evaluate the relationship between thyroid hormone levels and infarct severity in patients with ST-elevation myocardial infarction (STEMI).

methodsWe retrospectively reviewed thyroid hormone levels, infarct severity, and the extent of transmurality in 40 STEMI patients evaluated via contrast-enhanced cardiac magnetic resonance imaging.

resultsThe high triiodothyronine (T3) group (≥ 68.3 ng/dL) exhibited a significantly higher extent of transmural involvement (late transmural enhancement > 75% after administration of gadolinium contrast agent) than did the low T3 group (60% vs. 15%; p = 0.003). However, no significant difference was evident between the high- and low-thyroid-stimulating hormone/free thyroxine (FT4) groups. When the T3 cutoff level was set to 68.3 ng/dL using a receiver operating characteristic curve, the sensitivity was 80% and the specificity 68% in terms of differentiating between those with and without transmural involvement. Upon logistic regression analysis, high T3 level was an independent predictor of transmural involvement after adjustment for the presence of diabetes mellitus (DM) and the use of glycoprotein IIb/IIIa inhibitors (odds ratio, 40.62; 95% confidence interval, 3.29 to 502; p = 0.004).

conclusionsThe T3 level predicted transmural involvement that was independent of glycoprotein IIb/IIIa inhibitor use and DM positivity.

Indexed as

AgedArea Under CurveBiomarkersChi-Square DistributionContrast MediaCoronary AngiographyFemaleHumansLogistic ModelsMagnetic Resonance Imaging, CineMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionMyocardiumOdds RatioBiomarkersContrast MediaThyroxineTriiodothyronineMagnetic resonance imagingMyocardial infarctionTriiodothyronine

Identifiers

PMID25045293
PMCPMC4101592
OpenAlexW2128519329

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.