ReviewWiley interdisciplinary reviews. RNA
Noncoding RNAs and the borders of heterochromatin.
Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- The expression landscape and pangenome of long non-coding RNA in the fungal wheat pathogenMicrobial genomics · 2023Article
- Identification of circRNA-miRNA-mRNA network in luminal breast cancers by integrated analysis of microarray datasets.Frontiers in molecular biosciences · 2023Article
- Review
- Emerging roles of chromatin in the maintenance of genome organization and function in plants.Genome biology · 2017Review
- Tandem repeats of Allium fistulosum associated with major chromosomal landmarks.Molecular genetics and genomics : MGG · 2017Article
- Long non-coding RNA produced by RNA polymerase V determines boundaries of heterochromatin.eLife · 2016Article
- Epigenetics and aging.Science advances · 2016Review
- The proper connection between shelterin components is required for telomeric heterochromatin assembly.Genes & development · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Eukaryotic genomes contain long stretches of repetitive DNA sequences, which are the preferred sites for the assembly of heterochromatin structures. The formation of heterochromatin results in highly condensed chromosomal domains that limit the accessibility of DNA to the transcription and recombination machinery to maintain genome stability. Heterochromatin has the tendency to spread, and the formation of boundaries that block heterochromatin spreading is required to maintain stable gene expression patterns. Recent work has suggested that noncoding RNAs (ncRNAs) are involved in regulating boundary formation in addition to their well-established roles in chromatin regulation. Here, we present a review of our current understanding of the involvement of ncRNA at the boundaries of heterochromatin, highlighting their mechanisms of action in different settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.