Evidence map›Paper›PMID 25042872›Full record

ArticleStatistics in medicine2014

Variable selection in subdistribution hazard frailty models with competing risks data.

Il Do Ha, Minjung Lee, Seungyoung Oh, Jong-Hyeon Jeong, Richard Sylvester, Youngjo Lee

Abstract read
In one paragraph

Article in Statistics in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. High-Dimensional Survival Analysis: Methods and Applications.Annual review of statistics and its application · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Scalable Algorithms for Large Competing Risks Data.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Il Do HaDepartment of Data Management, Daegu Haany University, Gyeongsan, South Korea.
Minjung Lee
Seungyoung Oh
Jong-Hyeon Jeong
Richard Sylvester
Youngjo Lee

Funding

STUDY TO ASSESS RALOXIFENE FOR PREVENTING BREAST CANCERU10CA069974 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COSTANTINO, JOSEPH P. · 1995 to 2013
$62.4M
PRIMARY BREAST CANCER THERAPY--BIOSTATISTICS CENTERU10CA069651 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COSTANTINO, JOSEPH P. · 1995 to 2012
$52.1M
NCI NIH HHS 5-U10-CA69651-11NCI NIH HHS 5-U10-CA69974-09NCI NIH HHS U10 CA069651NCI NIH HHS U10 CA069974
6 · The paper itself

Abstract

The proportional subdistribution hazards model (i.e. Fine-Gray model) has been widely used for analyzing univariate competing risks data. Recently, this model has been extended to clustered competing risks data via frailty. To the best of our knowledge, however, there has been no literature on variable selection method for such competing risks frailty models. In this paper, we propose a simple but unified procedure via a penalized h-likelihood (HL) for variable selection of fixed effects in a general class of subdistribution hazard frailty models, in which random effects may be shared or correlated. We consider three penalty functions, least absolute shrinkage and selection operator (LASSO), smoothly clipped absolute deviation (SCAD) and HL, in our variable selection procedure. We show that the proposed method can be easily implemented using a slight modification to existing h-likelihood estimation approaches. Numerical studies demonstrate that the proposed procedure using the HL penalty performs well, providing a higher probability of choosing the true model than LASSO and SCAD methods without losing prediction accuracy. The usefulness of the new method is illustrated using two actual datasets from multi-center clinical trials.

Indexed as

Likelihood FunctionsProportional Hazards ModelsAgedBreast NeoplasmsComputer SimulationFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalTamoxifenUrinary Bladder NeoplasmsTamoxifencompeting risksfrailty modelsh-likelihood penalty functionpenalized h-likelihoodsubdistribution hazardvariable selection

Identifiers

PMID25042872
PMCPMC4190010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.