Observational studyOsteoarthritis and cartilage2014
Sedentary behavior and blood pressure control among osteoarthritis initiative participants.
Observational study in Osteoarthritis and cartilage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial.JAMA network open · 2024Trial
- A clinical model to predict the progression of knee osteoarthritis: data from Dryad.Journal of orthopaedic surgery and research · 2023Trial
- Sedentary behavior and compensatory mechanisms in response to different doses of exercise-a randomized controlled trial in overweight and obese adults.European journal of clinical nutrition · 2017Trial
- Reduced varying coefficient models for regional quantile regression with multiple responses.Biometrics · 2026Article
- Self-reported sedentary time and its influencing factors among patients with knee osteoarthritis: a cross-sectional survey.Scientific reports · 2025Article
- Associations of nonoccupational sedentary behaviors with cardiometabolic outcomes: coronary artery risk development in young adults (CARDIA).Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Circulating microRNAs as potential biomarkers of physical activity in geriatric patients with HCV.BMC molecular and cell biology · 2024Article
- Effect of Reducing Sedentary Behavior on Blood Pressure (RESET BP): Rationale, design, and methods.Contemporary clinical trials · 2021Article
- Buddhist Activities related to Sedentary behavior and Hypertension in Tibetan monks.Journal of human hypertension · 2019Article
- Relationship between objectively measured lifestyle factors and health factors in patients with knee osteoarthritis: The STROBE Study.Medicine · 2019Article
- Understanding Atherosclerosis Through an Osteoarthritis Data Set.Arteriosclerosis, thrombosis, and vascular biology · 2019Review
- The Impact of Exercise in Rodent Models of Chronic Pain.Current osteoporosis reports · 2018Review
- Knee Osteoarthritis and Risk of Hypertension: A Longitudinal Cohort Study.Rejuvenation research · 2018Article
- Incorporating Novel Mobile Health Technologies Into Management of Knee Osteoarthritis in Patients Treated With Intra-Articular Hyaluronic Acid: Rationale and Protocol of a Randomized Controlled Trial.JMIR research protocols · 2016Article
- Osteoarthritis year in review 2015: clinical.Osteoarthritis and cartilage · 2016Review
- Physical exercise as non-pharmacological treatment of chronic pain: Why and when.Best practice & research. Clinical rheumatology · 2015Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.
designWe conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and "elevated BP" defined as BP ≥ 130/85 mm Hg.
resultsFor this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69-7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.
conclusionA strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.