ArticleCancer2014
Substance use disorder and its effects on outcomes in men with advanced-stage prostate cancer.
Article in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Systematic review of healthcare costs related to mental health conditions among cancer survivors.Expert review of pharmacoeconomics & outcomes research · 2018Pooled it
- Substance use monitoring in supportive oncology: surveillance is not a clinical outcome, and policing is not a therapeutic framework.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- The association between the mental health disorders, substance abuse, and tobacco use with head & neck cancer stage at diagnosis.Cancer causes & control : CCC · 2025Article
- Care for patients with cancer and substance use disorders: a qualitative study of oncology team experiences.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Interventions for behavioral health comorbidities in the hospice setting: a scoping review.Annals of palliative medicine · 2024Article
- Association Between Alcohol Use Disorder and Hospital Readmission Rates and Outcomes in Cancer Survivors: A Population Cohort Study.Journal of the National Comprehensive Cancer Network : JNCCN · 2024Article
- Immunoassay Urine Drug Testing among Patients Receiving Opioids at a Safety-Net Palliative Medicine Clinic.Cancers · 2023Article
- Risks of alcohol and drug use disorders in prostate cancer survivors: a national cohort study.JNCI cancer spectrum · 2023Article
- Impact of modifiable lifestyle risk factors for prostate cancer prevention: a review of the literature.Frontiers in oncology · 2023Review
- Using health insurance claims data to assess long-term disease progression in a prostate cancer cohort.The Prostate · 2022Article
- Drug use disorder and risk of incident and fatal prostate cancer among Swedish men: a nationwide epidemiological study.Cancer causes & control : CCC · 2022Article
- Disease Prevalence and Fatality, Life History Strategies, and Behavioral Control of the COVID Pandemic.Evolutionary psychological science · 2022Article
- An Interdisciplinary Approach to Metastatic Pancreatic Cancer and Comorbid Opioid Use Disorder Treatment Within a VA Health Care System.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021Article
- Co-occurring substance use disorder: The impact on treatment adherence in women with locally advanced cervical cancer.Gynecologic oncology reports · 2019Article
- Association between age, substance use, and outcomes in Medicare enrollees with prostate cancer.Journal of geriatric oncology · 2016Article
- Identifying and assessing the risk of opioid abuse in patients with cancer: an integrative review.Substance abuse and rehabilitation · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSubstance use disorder in patients with cancer has implications for outcomes. The objective of this study was to analyze the effects of the type and timing of substance use on outcomes in elderly Medicare recipients with advanced prostate cancer.
methodsThis was an observational cohort study using Surveillance, Epidemiology, and End Results (SEER)-Medicare linked data from 2000 to 2009. Among men who were diagnosed with advanced prostate cancer between 2001 and 2004, we identified those who had a claim for substance use disorder in the year before cancer diagnosis, 1 year after cancer diagnosis, and an additional 4 years after diagnosis. The outcomes investigated were use of health services, costs, and mortality.
resultsThe prevalence of substance use disorder was 10.6%. The category drug psychoses and related had greater odds of inpatient hospitalizations (odds ratio [OR], 2.3; 95% confidence interval [CI], 1.9-2.8), outpatient hospital visits (OR, 2.6; 95% CI, 1.9-3.6), and emergency room visits (OR, 1.7; 95% CI, 1.2-2.4). Substance use disorder in the follow-up phase was associated with greater odds of inpatient hospitalizations (OR, 2.0; 95% CI, 1.8-2.2), outpatient hospital visits (OR, 2.0; 95% CI, 1.7-2.4), and emergency room visits (OR, 1.7; 95% CI, 1.5-2.1). Compared with men who did not have substance use disorder, those in the category drug psychoses and related had 70% higher costs, and those who had substance use disorder during the follow-up phase had 60% higher costs. The hazard of all-cause mortality was highest for patients in the drug psychoses and related category (hazard ratio, 1.3; 95% CI, 1.1-1.7) and the substance use disorder in treatment phase category (hazard ratio, 1.5; 95% CI, 1.3-1.7).
conclusionsThe intersection of advanced prostate cancer and substance use disorder may adversely affect outcomes. Incorporating substance use screening and treatments into prostate cancer care guidelines and coordination of care is desirable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.