ArticleCritical care (London, England)2014
Inflammation biomarkers and delirium in critically ill patients: new insights?
Article in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery.Bioscience reports · 2020Trial
- Blood-based biomarkers and delirium in critically ill adults in the ICU: a systematic review.Intensive care medicine experimental · 2026Review
- Review
- A nomogram model to predict postoperative delirium in esophageal cancer patients undergoing esophagectomy.BMC cancer · 2025Article
- Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Effects of Dexmedetomidine Combined with Sufentanil on Postoperative Delirium in Young Patients After General Anesthesia.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Neuroprotective effect of bispectral index-guided fast-track anesthesia using sevoflurane combined with dexmedetomidine for intracranial aneurysm embolization.Neural regeneration research · 2018Article
- Human herpesvirus 6B reactivation and delirium are frequent and associated events after cord blood transplantation.Bone marrow transplantation · 2015Article
- Prolonged mechanical ventilation-induced neuroinflammation affects postoperative memory dysfunction in surgical mice.Critical care (London, England) · 2015Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathophysiological mechanism of the serious and frequently occurring disorder delirium is poorly understood. Inflammation and sepsis are known risk factors for ICU delirium and therefore these patients are highly susceptible to delirium. Several studies have been performed to determine which cytokines are most associated with delirium but the results are inconclusive. Also, new biomarkers associated with brain dysfunction and cognitive impairment are still recognized and need to be studied to determine their relation with delirium. In this commentary we address some limitations concerning an interesting new study that warrants directions for future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.