Trial reportMuscle & nerve2015
Prospective study of muscle cramps in Charcot-Marie-tooth disease.
Trial report in Muscle & nerve, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Charcot-Marie-Tooth disease and related neuropathies.Nature reviews. Disease primers · 2026Review
- Review
- Novel mutation in theThe Journal of international medical research · 2022Article
- Phenotype of Patients With Charcot-Marie-Tooth With the p.His123Arg Mutation inNeurology. Genetics · 2021Article
- Pain Phenotypes in Rare Musculoskeletal and Neuromuscular Diseases.Neuroscience and biobehavioral reviews · 2021Review
- Satisfaction with ankle foot orthoses in individuals with Charcot-Marie-Tooth disease.Muscle & nerve · 2021Article
- Inferring Static Hand Poses from a Low-Cost Non-Intrusive sEMG Sensor.Sensors (Basel, Switzerland) · 2019Article
- The Charcot-Marie-Tooth Health Index: Evaluation of a Patient-Reported Outcome.Annals of neurology · 2018Article
- Whole genome sequencing identifies ANXA3 and MTHFR mutations in a large family with an unknown equinus deformity associated genetic disorder.Molecular biology reports · 2016Article
- Neurogenic muscle cramps.Journal of neurology · 2015Review
- The genetics of Charcot-Marie-Tooth disease: current trends and future implications for diagnosis and management.The application of clinical genetics · 2015Review
- Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study.Sleep science (Sao Paulo, Brazil)Article
- The impact of pain and nocturnal cramps on sleep quality in Charcot Marie Tooth disease: a case-control study.Sleep science (Sao Paulo, Brazil)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionThis study aims to assess the frequency, location, severity, duration, and fluctuation over time of muscle cramps in Charcot-Marie-Tooth disease (CMT).
methodsInherited Neuropathies Consortium Contact Registry participants recorded the occurrence and characteristics of muscle cramps using an 11-question survey administered 3 times over 8 weeks.
resultsA total of 110 adult patients with CMT completed the survey. Weekly cramp frequency was 9.3 (SD 12.3), and 23% had daily muscle cramps. Twenty-two percent reported a significant impact on quality of life. Over 8 weeks, the daily frequency and severity of muscle cramps did not change significantly.
conclusionsPatients with CMT have muscle cramps that vary little over an 8-week period, and they may interfere with quality of life. These data may be useful in the planning of clinical trials of agents to treat adults with CMT-associated muscle cramps.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.