ReviewCurrent opinion in microbiology2014
Recent insights into the evolution of innate viral sensing in animals.
Review in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Gene conversion generates evolutionary novelty that fuels genetic conflicts.Current opinion in genetics & development · 2019Review
- Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors.Viruses · 2019Review
- Strong selection of the TLR2 coding region among the Lagomorpha suggests an evolutionary history that differs from other mammals.Immunogenetics · 2019Article
- Evolution of toll-like receptors in the context of terrestrial ungulates and cetaceans diversification.BMC evolutionary biology · 2017Article
- Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Recognition of cytosolic DNA attenuates glucose metabolism and induces AMPK mediated energy stress response.International journal of biological sciences · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The evolution of viral sensors is likely to be shaped by the constraint imposed through high conservation of viral Pathogen-Associated Molecular Patterns (PAMPs), and by the potential for 'arms race' coevolution with more rapidly evolving viral proteins. Here we review the recent progress made in understanding the evolutionary history of two types of viral sensor, RNA helicases and Toll-like receptors. We find differences both in their rates of evolution, and in the levels of positive selection they experience. We suggest that positive selection has been the primary driver of the rapid evolution of the RNA helicases, while selective constraint has been a stronger influence shaping the slow evolution of the Toll-like receptors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.