Evidence map›Paper›PMID 25042039›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2014

Purkinje cell loss in essential tremor.

Elan D Louis, Phyllis L Faust

Abstract readLetterComment
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Six Myths and Misconceptions about Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Review
  6. Article
  7. Article
  8. Selective loss of the GABAJournal of neurophysiology · 2020
    Article
  9. Article
  10. Changes in Midline Tremor and Gait Following Deep Brain Stimulation for Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019
    Article
  11. Article
  12. Article
  13. Essential Tremor: A Common Disorder of Purkinje Neurons?The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2016
    Review
  14. Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis.Movement disorders : official journal of the Movement Disorder Society · 2016
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elan D LouisGH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Phyllis L Faust

Funding

Clinical Pathological Study of Cognitive Impairment in Essential TremorR01NS086736 · NINDS · YALE UNIVERSITY · PI COSENTINO, STEPHANIE ANN, LOUIS, ELAN D · 2014 to 2023
$8.1M
ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMORR01NS039422 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2000 to 2013
$7.7M
Identification of Susceptibility Genes for Essential TremorR01NS073872 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLARK, LORRAINE N, LOUIS, ELAN D · 2011 to 2019
$7.4M
GENETIC EPIDEMIOLOGY OF PARKINSONS DISEASER01NS036630 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARDER, KAREN S · 1998 to 2008
$6.8M
NEUROEPIDEMIOLOGY TRAINING PROGRAMT32NS007153 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GU, YIAN, WILLEY, JOSHUA ZEBADIAH · 1987 to 2023
$6.2M
Pathogenesis Of Essential Tremor: Cerebellar MetabolismR01NS042859 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOUIS, ELAN D · 2003 to 2012
$4.9M
in Vivo Quantification of Cerebellar GABA and NAA in Essential TremorR01NS085136 · NINDS · YALE UNIVERSITY · PI MATUSKEY, DAVID A · 2013 to 2017
$3.3M
Pathogenesis of Essential Tremor: Cerebellar MetabolismR56NS042859 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOUIS, ELAN D · 2008 to 2008
$500k
Essential Tremor: Gene expression profiling in cerebellar Purkinje cellsR21NS077094 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FAUST, PHYLLIS L · 2011 to 2012
$440k
NINDS NIH HHS R01 NS036630NINDS NIH HHS R01 NS039422NINDS NIH HHS R01 NS042859NINDS NIH HHS R01 NS073872NINDS NIH HHS R01 NS085136NINDS NIH HHS R01 NS086736NINDS NIH HHS R01 NS39422NINDS NIH HHS R21 NS077094NINDS NIH HHS R56 NS042859NINDS NIH HHS T32 NS007153
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CerebellumEssential TremorFemaleHumansMalePurkinje Cells

Identifiers

PMID25042039
PMCPMC4162819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.