Evidence map›Paper›PMID 25041824›Full record

ArticleMolecular oncology2014

Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast.

Salvatore Piscuoglio, Charlotte K Y Ng, Luciano G Martelotto, Carey A Eberle, Catherine F Cowell, Rachael Natrajan, François-Clement Bidard, Leticia De Mattos-Arruda, Paul M Wilkerson, Odette Mariani and 3 more

Open access · greenAbstract read
In one paragraph

Article in Molecular oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Invasive papillary carcinoma of the breast.Frontiers in oncology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Breast carcinomas of low malignant potential.Virchows Archiv : an international journal of pathology · 2022
    Review
  11. Papillary lesions of the breast.Virchows Archiv : an international journal of pathology · 2022
    Review
  12. Article
  13. Papillary neoplasms of the breast-reviewing the spectrum.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Review
  14. Article
  15. Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Review
  16. Article
  17. Article
  18. Assessment ofNPJ breast cancer · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Salvatore PiscuoglioDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Charlotte K Y NgDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Luciano G MartelottoDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Carey A EberleDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Catherine F CowellDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Rachael NatrajanThe Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK.
François-Clement BidardDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA; Institut Curie, Department of Biopathology and INSERM U934, Paris, France.
Leticia De Mattos-ArrudaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Paul M WilkersonThe Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK.
Odette MarianiInstitut Curie, Department of Biopathology and INSERM U934, Paris, France.
Anne Vincent-SalomonInstitut Curie, Department of Biopathology and INSERM U934, Paris, France. Electronic address: anne.salomon@curie.fr.
Britta WeigeltDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA.
Jorge S Reis-FilhoDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York 10065, NY, USA. Electronic address: reisfilj@mskcc.org.
Memorial Sloan Kettering Cancer Center · USInserm · FRInstitute of Cancer Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary carcinoma (PC) is a rare type of breast cancer, which comprises three histologic subtypes: encapsulated PC (EPC), solid PC (SPC) and invasive PC (IPC). Microarray-based gene expression and Affymetrix SNP 6.0 gene copy number profiling, and RNA-sequencing revealed that PCs are luminal breast cancers that display transcriptomic profiles distinct from those of grade- and estrogen receptor (ER)-matched invasive ductal carcinomas of no special type (IDC-NSTs), and that the papillary histologic pattern is unlikely to be underpinned by a highly recurrent expressed fusion gene or a highly recurrent expressed mutation. Despite displaying similar patterns of gene copy number alterations, significant differences in the transcriptomic profiles of EPCs, SPCs and IPCs were found, and may account for their different histologic features.

Indexed as

Breast NeoplasmsCarcinoma, PapillaryFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticGenomicsHumansImmunohistochemistryIn Vitro TechniquesPolymorphism, Single NucleotideFusion geneMicroarraysMutationRNA-sequencingSingle nucleotide polymorphism arrays

Identifiers

PMID25041824
PMCPMC5037246
OpenAlexW2151093629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.