Evidence map›Paper›PMID 25041351›Full record

ReviewPhotochemistry and photobiology

Chemical and biological mechanisms of pathogen reduction technologies.

Janna M Mundt, Lindsay Rouse, Jeroen Van den Bossche, Raymond P Goodrich

Abstract readReview
In one paragraph

Review in Photochemistry and photobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Pathogens (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Review
  5. Near-Infrared Dyes: Towards Broad-Spectrum Antivirals.International journal of molecular sciences · 2022
    Review
  6. Latest Advances in 3D Bioprinting of Cardiac Tissues.Advanced materials technologies · 2022
    Article
  7. Article
  8. Article
  9. Improvement of Blood Processing and Safety by Automation and Pathogen Reduction Technology.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Photodynamic Inactivation ofAntibiotics (Basel, Switzerland) · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janna M MundtTerumo BCT, Lakewood, CO.
Lindsay Rouse
Jeroen Van den Bossche
Raymond P Goodrich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the last decade new technologies have been developed and implemented which employ light, often in the presence of a photosensitizer, to inactivate pathogens that reside in human blood products for the purpose of transfusion. These pathogen reduction technologies attempt to find the proper balance between pathogen kill and cell quality. Each system utilizes various chemistries that not only impact which pathogens they can inactivate and how, but also how the treatments affect the plasma and cellular proteins and to what degree. This paper aims to present the various chemical mechanisms for pathogen reduction in transfusion medicine that are currently practiced or in development.

Indexed as

PhotopheresisBacteriaBlood TransfusionFurocoumarinsHumansLightMethylene BluePhotosensitizing AgentsRiboflavinTrypanosomaVirusesamotosalenFurocoumarinsMethylene BluePhotosensitizing AgentsRiboflavin

Identifiers

PMID25041351
PMCPMC4277684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.