ArticleExperimental dermatology2014
Novel gene identified in an exome-wide association study of tanning dependence.
Article in Experimental dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Recent-Onset Melanoma and the Implications of the Excessive Use of Tanning Devices-Case Report and Review of the Literature.Medicina (Kaunas, Lithuania) · 2024Review
- Cutaneous Photoprotection: A Review of the Current Status and Evolving Strategies.The Yale journal of biology and medicine · 2020Review
- Genetic Associations with Indoor Tanning Addiction among non-Hispanic White Young Adult Women.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020Article
- Influence of maternal and own genotype at tanning dependence-related SNPs on sun exposure in childhood.BMC medical genetics · 2018Article
- Interdisciplinary Perspectives on Sun Safety.JAMA dermatology · 2018Review
- [Superbrown beauty : The surface of tanorexia and tanning dependence].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017Review
- Indoor Tanning Dependence in Young Adult Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Article
- Assessing risk for Mendelian disorders in a Bronx population.Molecular genetics & genomic medicine · 2017Article
- Pigmentary traits and use of indoor tanning beds in a cohort of women.The British journal of dermatology · 2017Article
- Indoor tanning bed use and risk of food addiction based on the modified Yale Food Addiction Scale.Journal of biomedical research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Growing evidence suggests that some individuals may exhibit symptoms of dependence to ultraviolet light, a known carcinogen, in the context of tanning. Genetic associations with tanning dependence (TD) have not yet been explored. We conducted an exome-wide association study in 79 individuals who exhibited symptoms of TD and 213 individuals with volitional exposure to ultraviolet light, but who were not TD based on three TD scales. A total of 300 000 mostly exomic single nucleotide polymorphisms primarily in coding regions were assessed using an Affymetrix Axiom array. We performed a gene burden test with Bonferroni correction for the number of genes examined (P < 0.05/14 904 = 3.36 × 10(-6) ). One gene, patched domain containing 2 (PTCHD2), yielded a statistically significant P-value of 2.5 × 10(-6) (OR = 0.27) with fewer individuals classified as TD having a minor allele at this locus. These results require replication, but are the first to support a specific genetic association with TD.
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Registered trials
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