ArticlePediatric diabetes2015
A decade of temporal trends in overweight/obesity in youth with type 1 diabetes after the Diabetes Control and Complications Trial.
Article in Pediatric diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- The Role of Protein and Fat Intake on Insulin Therapy in Glycaemic Control of Paediatric Type 1 Diabetes: A Systematic Review and Research Gaps.Nutrients · 2021Pooled it
- Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association.Diabetes care · 2018Guideline
- Trial
- Clinical, Psychosocial, and Demographic Factors Are Associated With Overweight and Obesity in Early Adolescent Girls With Type 1 Diabetes.The Diabetes educator · 2016Trial
- Improving dietary quality in youth with type 1 diabetes: randomized clinical trial of a family-based behavioral intervention.The international journal of behavioral nutrition and physical activity · 2015Trial
- High Waist-to-Height Ratio Increases the Risk of Cardiovascular Outcomes in Adults with Type 1 Diabetes Mellitus: A Nationwide Cohort Study.Diabetes & metabolism journal · 2026Article
- Global prevalence and factors associated with overweight and obesity in children and adolescents with type 1 diabetes: a systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2025Review
- Article
- Article
- Sociodemographic inequities and use of hybrid closed-loop systems associated with obesity in youth with type 1 diabetes.Diabetes research and clinical practice · 2025Article
- BMI trajectories among children diagnosed with type 1 diabetes mellitus at a tertiary diabetes center.Frontiers in endocrinology · 2025Article
- Case Report: Insulin resistance in type 1 diabetes mellitus: the role of genetic factors.Frontiers in endocrinology · 2025Article
- 24-h energy expenditure in people with type 1 diabetes: impact on equations for clinical estimation of energy expenditure.European journal of clinical nutrition · 2024Article
- Epidemiology of type 1 diabetes mellitus in children and adolescents: A 50-year, single-center experience.Journal of diabetes · 2024Article
- Cardiovascular Risk Factors in Adolescents with Type 1 Diabetes: Prevalence and Gender DifferencesJournal of clinical research in pediatric endocrinology · 2024Article
- The emergence of obesity in type 1 diabetes.International journal of obesity (2005) · 2024Review
- Weight Management Behaviors are Associated with Elevated Glycemic Outcomes in Adolescents and Young Adults with Type 1 Diabetes.Journal of clinical psychology in medical settings · 2023Article
- The Burden of Obesity in Type 1 Diabetic Subjects: A Sex-specific Analysis From the AMD Annals Initiative.The Journal of clinical endocrinology and metabolism · 2023Article
- Effect of Asanas in Yoga on Intraocular Pressure of Practicing Healthy Individuals: a Prospective Observational Study.Maedica · 2023Article
- Highlighting the Role of Obesity and Insulin Resistance in Type 1 Diabetes and Its Associated Cardiometabolic Complications.Current obesity reports · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundYouth with type 1 diabetes (T1D) are at risk for weight gain due to the epidemic of childhood overweight/obesity and common use of intensive insulin therapy; the latter resulted in weight gain in the Diabetes Control and Complications Trial.
objectiveTo assess overweight/obesity prevalence and intensive insulin therapy use in youth with T1D over a decade and identify factors associated with weight status and glycemic control.
methodsWe obtained cross-sectional data from four unique cohorts (1999, 2002, 2006, and 2009). Youth (N = 507, 49% male) were 8-16 yr old with T1D duration ≥6 months, A1c 6.0-12.0% (42-108 mmol/mol), and daily insulin dose ≥0.5 U/kg.
resultsAcross cohorts, age, body mass index (BMI) percentile, and A1c ranged from 12.0 ± 2.2 to 12.8 ± 2.3 yr, 70 ± 22 to 72 ± 21, and 8.3 ± 1.0 (67 ± 11) to 8.5 ± 1.1% (69 ± 12 mmol/mol), respectively. Intensive insulin therapy use increased from 52 to 97% (p < 0.001) between 1999 and 2009. However, prevalence of overweight/obesity remained similar, 27% (1999), 36% (2002), 33% (2006), and 31% (2009) (p = 0.54), as did z-BMI. In multivariate analysis, higher A1c was related to higher insulin dose (p < 0.01), less frequent blood glucose monitoring (p < 0.001), and non-white race (p < 0.001); A1c was not related to z-BMI, intensive insulin therapy, or cohort. z-BMI was related to insulin dose (p < 0.005) but not intensive insulin therapy or cohort.
conclusionsDespite near-universal implementation of intensive insulin therapy, overweight/obesity prevalence in youth with T1D remained stable over a decade, similar to the general pediatric population. However, A1c remained suboptimal, underscoring the need to optimize T1D treatment to reduce future complication risk.
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