ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2014
Spectral-domain optical coherence tomography findings in pediatric tilted disc syndrome.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Automated segmentation and quantification of peripapillary hyperreflective ovoid mass-like structures using swept-source optical coherence tomography.BMC ophthalmology · 2026Article
- Peripapillary Hyperreflective Ovoid Mass-Like Structure as an Optic Disc Pseudo-Edema Case Report and Review.Case reports in ophthalmological medicine · 2026Article
- The Observation of Peripapillary Hyperreflective Ovoid Mass-Like Structures in Adolescents by Swept-Source Optical Coherence Tomography Angiography.Translational vision science & technology · 2025Article
- Peripapillary choroidal vascularity of paediatric myopic eyes with peripapillary hyperreflective ovoid mass-like structures.Acta ophthalmologica · 2025Article
- Diagnostic dilemma of papilledema and pseudopapilledema.International ophthalmology · 2024Review
- Clinical characteristics of peripapillary hyperreflective ovoid mass-like structures in myopic children.International journal of ophthalmology · 2024Article
- Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases.Frontiers in neurology · 2024Review
- Deep Optic Nerve Head Morphology in Tilted Disc Syndrome and Its Clinical Implication on Visual Damage.Investigative ophthalmology & visual science · 2023Article
- Are PHOMS a clinical sign of optic neuritis?Eye (London, England) · 2023Article
- Morphology and microcirculation changes of the optic nerve head between simple high myopia and pathologic myopia.BMC ophthalmology · 2023Article
- Diagnosis of Optic Disc Oedema: Fundus Features, Ocular Imaging Findings, and Artificial Intelligence.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Peripapillary hyperreflective ovoid mass-like structures: Multimodal imaging-A review.Clinical & experimental ophthalmology · 2023Review
- Peripapillary hyper-reflective ovoid mass-like structures (PHOMS): clinical significance, associations, and prognostic implications in ophthalmic conditions.Frontiers in neurology · 2023Review
- Volumetric Measurement of Peripapillary Hyperreflective Ovoid Masslike Structures in Patients with Optic Disc Drusen.Ophthalmology science · 2022Article
- Clinical and Multi-Mode Imaging Features of Eyes With Peripapillary Hyperreflective Ovoid Mass-Like Structures.Frontiers in medicine · 2022Article
- Peripapillary Hyper-reflective Ovoid Mass-like Structure (PHOMS): An Optical Coherence Tomography Marker of Axoplasmic Stasis in the Optic Nerve Head.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2021Article
- OCT Based Interpretation of the Optic Nerve Head Anatomy and Prevalence of Optic Disc Drusen in Patients with Idiopathic Intracranial Hypertension (IIH).Life (Basel, Switzerland) · 2021Article
- Peripapillary hyperreflective ovoid mass-like structures (PHOMS): OCTA may reveal new findings.Eye (London, England) · 2021Article
- Diagnosing Optic Disc Drusen in the Modern Imaging Era: A Practical Approach.Neuro-ophthalmology (Aeolus Press) · 2021Review
- ODTiD: Optic Nerve Head SD-OCT Image Dataset.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report a novel spectral-domain optical coherence tomography (SD-OCT) finding in children affected by tilted disc syndrome (TDS), and to correlate it with early visual field defects.
methodsPatients between 5 and 17 years old with TDS were enrolled in this study. The diagnosis of TDS was made by stereoscopic fundus photography, when the upper edge of the optic disc protruded anteriorly relative to its lower edge. All eyes were examined with 12 radial SD-OCT B-scans of 12 mm centered on the optic disc; the fundus area encompassing the optic nerve was additionally scanned using several vertical and horizontal scans.. C-scan SD-OCT were acquired using the Macular Cube 512 x 128 to create the en face image. Standard automated perimetry 24-2 tests were performed on all patients.
resultsThirty-eight eyes of 20 pediatric patients with TDS syndrome were enrolled during this 24-months clinical trial. Their mean age was 10.9 ± 2.7 years (range 7-15 years), 12 (60%) were male and eight (40%) were female. The OCT images of the optic discs showed a protrusion of the upper edge of Bruch's membrane and choroid at the nasal edge of the optic disc in 39.5% of the eyes. The retinal nerve fiber tissue appeared to be herniated into this protrusion and bent superiorly in 15 eyes. This severe bending corresponded to early visual field anomalies that were not reduced by corrective lenses in 46.7% of the eyes.
conclusionVisual field defects that do not improve by increased myopic correction in TDS may be due to the severe bending of the retinal nerve fiber tissue, which would impair axonal flow.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.