Evidence map›Paper›PMID 25038854›Full record

ArticleEuropean radiology2014

Diffusion-weighted MR imaging for the diagnosis of abscess complicating fistula-in-ano: preliminary experience.

Anthony Dohan, Clarisse Eveno, Raluca Oprea, Karine Pautrat, Vinciane Placé, Marc Pocard, Christine Hoeffel, Mourad Boudiaf, Philippe Soyer

Abstract read
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In one paragraph

Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. [Perianal Fistula: An Overview].Journal of the Korean Society of Radiology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Elucidating vaginal fistulas on CT and MRI.Insights into imaging · 2019
    Review
  14. Article
  15. Observational
  16. Review
  17. Article
  18. Article
  19. Article
  20. Perianal Fistula With and Without Abscess: Assessment of Fistula Activity Using Diffusion-Weighted Magnetic Resonance Imaging.Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Anthony DohanDepartment of Body and Interventional Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France, anthony.dohan@lrb.aphp.fr.
Clarisse Eveno
Raluca Oprea
Karine Pautrat
Vinciane Placé
Marc Pocard
Christine Hoeffel
Mourad Boudiaf
Philippe Soyer
Assistance Publique – Hôpitaux de Paris · FRHôpital Lariboisière · FRDélégation Paris 7 · FRHôpital Robert-Debré · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in the diagnosis of abscess-complicating fistula-in-ano.

methodsThis retrospective study was approved by our Institutional Review Board and informed consent was waived. MRI examinations, including fat-suppressed T2-weighted turbo spin-echo (T2-TSE) MRI and DWMRI, of 24 patients with a fistula-in-ano, were reviewed by two independent readers for the presence and number of visible fistulas, conspicuity and apparent diffusion coefficient (ADC) measurement of suspected fistula tracks and pelvic collections. The reference standard was surgical with follow-up findings.

resultsSensitivity was 91.2 % [95 % CI: 76 %-98 %] for T2-weighted TSE MRI and 100 % [95 % CI: 90 %-100 %] for DWMRI detecting fistulas. ADC values were lower in abscesses than in inflammatory masses (P = 0.714.10(-6)). The area under the ROC curve was 0.971 and the optimal cut-off ADC value was 1.186 × 10(-3) mm(2)/s, yielding a sensitivity of 100 % [95 % CI: 77 %-100 %], a specificity of 90 % [95 % CI: 66 %-100 %], a positive predictive value of 93 % [95 % CI: 82.8 %-100 %] and a negative predictive value of 90 % [95 % CI: 78 %-100 %] for an abscess diagnosis. Fistula conspicuity was greater with DWMRI than with T2-TSE MRI for the two observers (P = 0.0034 and P = 0.0007).

conclusionDWMRI shows high sensitivity and specificity for the diagnosis of perianal abscesses and helps discriminate between an abscess and inflammatory mass. Conspicuity of fistulas-in-ano is greater with DWMRI than with T2-weighted TSE MRI. KEY POINTS: • DWMRI can differentiate between pelvic abscess and inflammatory mass. • DWMRI helps avoid gadolinium-chelate administration in patients with a suspected fistula-in-ano. • DWMRI provides high degrees of conspicuity for fistula-in-ano. • Conspicuity of fistulas is better with DWMRI imaging than with T2-TSE-weighted MRI.

Indexed as

AbscessAdultAgedContrast MediaDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPelvisRectal FistulaRetrospective StudiesROC CurveYoung AdultContrast Media

Identifiers

PMID25038854
OpenAlexW2074215642

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.