ArticleEnvironmental research2014
Farm residence and lymphohematopoietic cancers in the Iowa Women's Health Study.
Article in Environmental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
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- Living in the vicinity of pesticide-treated crop fields: Exploring associated perceptions and psychological aspects in relation to self-reported and registry-based health symptoms.BMC psychology · 2024Article
- Evaluating the accuracy of satellite-based methods to estimate residential proximity to agricultural crops.Journal of exposure science & environmental epidemiology · 2024Article
- Evaluating the accuracy of satellite-based methods to estimate residential proximity to agricultural crops.Journal of exposure science & environmental epidemiology · 2024Article
- Mycotoxins and Amyotrophic Lateral Sclerosis: Food Exposure, Nutritional Implications and Dietary Solutions.CNS & neurological disorders drug targets · 2024Review
- Incidence and Risk Factors of Acute Leukemias in Armenia: A Population-Based Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Pesticide use and risk of systemic autoimmune diseases in the Agricultural Health Study.Environmental research · 2022Article
- Epidemiology of acute myeloid leukemia in Virginia: Excellent survival outcomes for patients in rural Appalachia.Cancer reports (Hoboken, N.J.) · 2021Article
- Impact of residential mobility on estimated environmental exposures in a prospective cohort of older women.Environmental epidemiology (Philadelphia, Pa.) · 2020Article
- An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study.Journal of exposure science & environmental epidemiology · 2019Article
- Urban vs rural residency and allergy prevalence among adult women: Iowa Women's Health Study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018Article
- Comparison of cancer incidence in Australian farm residents 45 years and over, compared to rural non-farm and urban residents - a data linkage study.BMC cancer · 2018Article
- Personal samplers of bioavailable pesticides integrated with a hair follicle assay of DNA damage to assess environmental exposures and their associated risks in children.Mutation research. Genetic toxicology and environmental mutagenesis · 2017Article
- Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis.Environmental health : a global access science source · 2017Article
- Cancer risks in a population-based study of 70,570 agricultural workers: results from the Canadian census health and Environment cohort (CanCHEC).BMC cancer · 2017Article
- Nonoccupational exposure to agricultural work and risk of urinary bladder cancer among Egyptian women.Archives of environmental & occupational health · 2017Article
- Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data.Environmental health perspectives · 2017Article
- Agricultural crop exposure and risk of childhood cancer: new findings from a case-control study in Spain.International journal of health geographics · 2016Article
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundCancer incidence in male farmers has been studied extensively; however, less is known about risk among women residing on farms or in agricultural areas, who may be exposed to pesticides by their proximity to crop fields. We extended a previous follow-up of the Iowa Women's Health Study cohort to examine farm residence and the incidence of lymphohematopoietic cancers. Further, we investigated crop acreage within 750 m of residences, which has been associated with higher herbicide levels in Iowa homes.
methodsWe analyzed data for a cohort of 37,099 Iowa women aged 55-69 years who reported their residence location (farm, rural (not a farm), town size based on population) at enrollment in 1986. We identified incident lymphohematopoietic cancers (1986-2009) by linkage with the Iowa Cancer Registry. Using a geographic information system, we geocoded addresses and calculated acreage of pasture and row crops within 750 m of homes using the 1992 National Land Cover Database. Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) in multivariate analyses of cancer risk in relation to both residence location and crop acreage.
resultsAs found in an earlier analysis of residence location, risk of acute myeloid leukemia (AML) was higher among women living on farms (HR=2.23, 95%CI: 1.25-3.99) or rural areas (but not on a farm) (HR=1.95, 95%CI: 0.89-4.29) compared with women living in towns of >10,000 population. We observed no association between farm or rural residence and non-Hodgkin lymphoma (NHL; overall or for major subtypes) or multiple myeloma. In analyses of crop acreage, we observed no association between pasture or row crop acreage within 750 m of homes and risk of leukemia overall or for the AML subtype. Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) risk was nonsignificantly elevated among women with pasture acreage within 750 m of their home (HRs for increasing tertiles=1.8, 1.8 and 1.5) and with row crop acreage within 750 m (HRs for increasing tertiles of acreage=1.4, 1.5 and 1.6) compared to women with no pasture or row crop acreage, respectively.
conclusionsIowa women living on a farm or in a rural area were at increased risk of developing AML, which was not related to crop acreage near the home. Living near pasture or row crops may confer an increased risk of CLL/SLL regardless of residence location. Further investigation of specific farm-related exposures and these cancers among women living on farms and in agricultural areas is warranted.
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