ArticleMolecular cell2014
RNA binding of PRC2: promiscuous or well ordered?
Article in Molecular cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- A novel partnership between lncTCF7 and SND1 regulates the expression of the TCF7 gene via recruitment of the SWI/SNF complex.Scientific reports · 2024Article
- H3K27me3-mediated epigenetic regulation in pluripotency maintenance and lineage differentiation.Cell insight · 2024Review
- Regulatory RNAs: role as scaffolds assembling protein complexes and their epigenetic deregulation.Exploration of targeted anti-tumor therapy · 2024Review
- LncRNAs in Cancer: From garbage to Junk.Cancers · 2020Review
- Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease.Diabetologia · 2019Article
- Molecular pattern of lncRNAs in hepatocellular carcinoma.Journal of experimental & clinical cancer research : CR · 2019Review
- Article
- Exploring the mechanisms behind long noncoding RNAs and cancer.Non-coding RNA research · 2018Review
- Structure of the PRC2 complex and application to drug discovery.Acta pharmacologica Sinica · 2017Review
- Article
- TUG1: a pivotal oncogenic long non-coding RNA of human cancers.Cell proliferation · 2016Review
- The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.RNA (New York, N.Y.) · 2015Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The polycomb repressive complex 2 (PRC2) methylates histones for epigenetic silencing and associates with thousands of protein-coding and noncoding RNAs. How the recruitment of PRC2 to specific sites is facilitated is currently unclear. Two recent studies have deciphered the impact of RNA binding on PRC2 recruitment and activity (Cifuentes-Rojas et al., 2014; Davidovich et al., 2013).
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Identifiers
25038410What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.