Evidence map›Paper›PMID 25038305›Full record

ArticleBiological psychology2014

Pre-pregnancy obesity and maternal circadian cortisol regulation: Moderation by gestational weight gain.

Nicki L Aubuchon-Endsley, Margaret H Bublitz, Laura R Stroud

Abstract read
In one paragraph

Article in Biological psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  8. Observational
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  12. Article
  13. CRH as a Predictor of Preterm Birth in Minority Women.Biological research for nursing · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicki L Aubuchon-EndsleyDepartment of Psychology, Idaho State University, 921 S 8th Avenue, Stop 8112, Pocatello, ID 83209, USA. Electronic address: Nicki_Aubuchon-Endsley@brown.edu.
Margaret H BublitzCenters for Behavioral and Preventive Medicine, 164 Summit Avenue, Providence, RI 02906, USA; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Box G-BH, Providence, RI 02912, USA. Electronic address: mbublitz@lifespan.org.
Laura R StroudCenters for Behavioral and Preventive Medicine, 164 Summit Avenue, Providence, RI 02906, USA; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Box G-BH, Providence, RI 02912, USA. Electronic address: Laura_Stroud@brown.edu.

Funding

Training in Behavioral & Preventive MedicineT32HL076134 · NHLBI · MIRIAM HOSPITAL · PI John Graham Thomas · 2006 to 2026
$5.7M
Maternal Depression Placental HPA Regulation & Fetal-Neonatal Stress ResponseR01MH079153 · NIMH · MIRIAM HOSPITAL · PI STROUD, LAURA R · 2007 to 2011
$3.2M
NHLBI NIH HHS 2T32HL076134-07NHLBI NIH HHS T32 HL076134NIMH NIH HHS R01 MH079153NIMH NIH HHS R01MH079153
6 · The paper itself

Abstract

We investigated main and interactive effects of maternal pre-pregnancy obesity and gestational weight gain on circadian cortisol from the second to third trimester. A diverse sample of 215 pregnant women was enrolled. Maternal height and most recent pre-pregnancy weight were collected at study initiation (22% obese). Weight and circadian salivary cortisol samples were measured during second (24±4) and third (35±1 weeks) trimesters. During the third trimester, women who were obese prior to conception showed elevated evening cortisol versus normal weight women. This pattern was moderated by weight gain in excess of Institute of Medicine guidelines, such that women who were obese prior to conception and gained greater than 7.94kg by the 35±1 week visit displayed greatest elevations in evening cortisol. Given links between excessive prenatal glucocorticoid exposure and both poor maternal and offspring health outcomes, elevated maternal cortisol may be one mechanism underlying links between maternal obesity and adverse perinatal outcomes.

Indexed as

Circadian RhythmWeight GainAdultBody Mass IndexBody WeightFemaleHumansHydrocortisoneObesityPregnancyPregnancy ComplicationsPregnancy Trimester, SecondPregnancy Trimester, ThirdSalivaUnited StatesYoung AdultHydrocortisoneCortisolGlucocorticoidObesityPregnancyWeight gain

Identifiers

PMID25038305
PMCPMC4157070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.