ArticleApplied and environmental microbiology2014
Microcystin production and regulation under nutrient stress conditions in toxic microcystis strains.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.
- Effects of Nutrient Limitation on the Synthesis of N-Rich Phytoplankton Toxins: A Meta-Analysis.Toxins · 2020Pooled it
- Nutrient disturbance in a shallow aquaculture pond impacts Microcystis gene expression but does not impact bacterial community function during bloom conditions.Journal of phycology · 2026Article
- Phytoplankton growth and potential cyanotoxin production differ in response to nitrogen and phosphorus amendments in late summer communities from Kabetogama Lake (Minnesota, United States).Journal of phycology · 2026Article
- Nutrient-driven regulation of saxitoxin gene expression and toxin production in Raphidiopsis raciborskii (Cyanobacteria).Journal of phycology · 2025Article
- Elucidation of Mechanisms by Which Microplastics (PET) Facilitates the Rapid Growth of Benthic Cyanobacteria and Toxin Production in Aquatic Ecosystems.Metabolites · 2025Review
- Global Occurrence of Cyanotoxins in Drinking Water Systems: Recent Advances, Human Health Risks, Mitigation, and Future Directions.Life (Basel, Switzerland) · 2025Review
- Cyanobacteria gene expression in response to environmental stress and seasonal changes.World journal of microbiology & biotechnology · 2025Article
- Intraspecific divergence withinProceedings. Biological sciences · 2025Article
- Extensive Genomic Rearrangement of Catalase-Less Cyanobloom-Forming Microcystis aeruginosa in Freshwater Ecosystems.Journal of microbiology (Seoul, Korea) · 2024Review
- Article
- Temporal Dynamics of Cyanobacterial Bloom Community Composition and Toxin Production from Urban Lakes.ACS ES&T water · 2024Article
- The Microcystis-microbiome interactions: origins of the colonial lifestyle.FEMS microbiology ecology · 2024Article
- Microbiome analysis revealsApplied and environmental microbiology · 2024Article
- The use of a benign fast-growing cyanobacterial species to control microcystin synthesis fromFrontiers in microbiology · 2024Article
- Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis.World journal of microbiology & biotechnology · 2023Review
- Nitrogen forms and concentration influence the impact of titanium dioxide nanoparticles on the biomass and antioxidant enzyme activities of Microcystis aeruginosa.Archives of microbiology · 2023Article
- The Influence of Micronutrient Trace Metals onToxins · 2022Article
- Review
- Article
- Entner-Doudoroff pathway inFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microcystin is a common and well-known cyanobacterial toxin whose intracellular role is still under investigation. Increasing knowledge on microcystin gene expression and regulation can contribute to the understanding of its putative cellular function. In this work, reverse transcription-quantitative PCR (RT-qPCR) was used to investigate the transcriptional response of the mcyD gene to nitrogen (nitrate and ammonium) and phosphorus limitation in two toxic Microcystis strains. The existence of a direct correlation between transcripts of mcyD and ntcA genes was also identified. In previous studies, NtcA (global nitrogen regulator) has been described as a potential component in the control of microcystin biosynthesis. This research showed that stress agents linked to nutrient deprivation could lead to a significant increase of microcystin production in both strains studied. The more toxic strain proved to be more resistant to nutrient limitation. The similar outcomes of mcyD regulation observed for all nutrients suggest that this response can be linked to oxidative stress of cells undergoing adverse growth conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.