Evidence map›Paper›PMID 25037617›Full record

Trial reportThe Journal of thoracic and cardiovascular surgery2014

Technical performance score is associated with outcomes after the Norwood procedure.

Meena Nathan, Lynn A Sleeper, Richard G Ohye, Peter C Frommelt, Christopher A Caldarone, James S Tweddell, Minmin Lu, Gail D Pearson, J William Gaynor, Christian Pizarro and 14 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The Journal of thoracic and cardiovascular surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Is There a Unified Etiology of Hypoplastic Left Heart Syndrome? Evaluating Genetic, Structural, and Hemodynamic Models of Disease Initiation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Observational
  14. The Pediatric Heart Network Residual Lesion Score Study: Design and objectives.The Journal of thoracic and cardiovascular surgery · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Meena NathanChildren's Hospital Boston and Harvard Medical School, Boston, Mass. Electronic address: meena.nathan@cardio.chboston.org.
Lynn A SleeperCytel Inc, Cambridge, Mass.
Richard G OhyeUniversity of Michigan Medical School, Ann Arbor, Mich.
Peter C FrommeltChildren's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wis.
Christopher A CaldaroneHospital for Sick Children, Toronto, Ontario, Canada.
James S TweddellChildren's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wis.
Minmin LuNew England Research Institutes, Watertown, Mass.
Gail D PearsonNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md.
J William GaynorChildren's Hospital of Philadelphia and University of Pennsylvania Medical School, Philadelphia, Pa.
Christian PizarroNemours Cardiac Center, Wilmington, Del.
Ismee A WilliamsMorgan Stanley Children's Hospital of NewYork-Presbyterian, New York, NY.
Steven D ColanChildren's Hospital Boston and Harvard Medical School, Boston, Mass; New England Research Institutes, Watertown, Mass.
Carolyn Dunbar-MastersonChildren's Hospital Boston and Harvard Medical School, Boston, Mass.
Peter J GruberUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.
Kevin HillDuke University, Chapel Hill, NC.
Jennifer Hirsch-RomanoUniversity of Michigan Medical School, Ann Arbor, Mich.
Jeffrey P JacobsJohns Hopkins All Children's Heart Institute, St Petersburg, Fla.
Jonathan R KaltmanNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md.
S Ram KumarChildren's Hospital Los Angeles, Los Angeles, Calif.
David MoralesCincinnati Children's Medical Center, Cincinnati, Ohio.
Scott M BradleyMedical University of South Carolina, Charleston, SC.
Kirk KanterEmory University, Atlanta, Ga.
Jane W NewburgerChildren's Hospital Boston and Harvard Medical School, Boston, Mass.
Pediatric Heart Network Investigators

Funding

Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
ZINC GLUCONATE GLYCINE LOZENGES &VITAMIN C EFFECTS ON COMMON COLDM01RR000042 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RUBENFIRE, MELVYN · 1985 to 2007
$40.8M
Ventricular Volumes and Varability (VVV)U01HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI SLEEPER, LYNN A · 2001 to 2010
$40.3M
Pediatric Heart Network: Follow-up of the Single Ventricle Reconstruction TrialU01HL068290 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAI, WYMAN W · 2001 to 2010
$4.1M
Pediatric Heart Disease Network: CHOP MembershipU01HL068279 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI VETTER, VICTORIA L · 2001 to 2010
$3.7M
Randomized Therapeutic Trials in Pediatric Heart DiseaseU01HL068285 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI NEWBURGER, JANE W. · 2001 to 2010
$3.4M
Randomized Clinical Trials for Pediatric Heart DiseaseU01HL068281 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SAUL, J PHILIP · 2001 to 2010
$3.2M
Clinical and genomic responses to remote ischemic preconditioningU01HL068288 · NHLBI · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI MCCRINDLE, BRIAN W · 2001 to 2010
$3.0M
Intermountain Pediatric Heart Disease Research CenterU01HL068292 · NHLBI · UNIVERSITY OF UTAH · PI MINICH, L. LUANN · 2001 to 2010
$2.7M
Randomized Trial of Nonflouroscopic Technologies in Pediatric SVT AblationU10HL109816 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI NEWBURGER, JANE W., TRIEDMAN, JOHN K · 2011 to 2015
$2.6M
The Duke-UNC-CH Pediatric Cardiology Clinical CenterU01HL068269 · NHLBI · DUKE UNIVERSITY · PI LI, JENNIFER S · 2001 to 2010
$2.6M
Pediatric Heart Network Prairieland ConsortiumU10HL109673 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CNOTA, JAMES, PAYNE, RONALD MARK · 2011 to 2015
$2.3M
NCRR NIH HHS M01 RR000042NHLBI NIH HHS HL068269NHLBI NIH HHS HL068270NHLBI NIH HHS HL068279NHLBI NIH HHS HL068281NHLBI NIH HHS HL068285NHLBI NIH HHS HL068288NHLBI NIH HHS HL068290NHLBI NIH HHS HL068292NHLBI NIH HHS HL085057NHLBI NIH HHS HL109737NHLBI NIH HHS HL109781NHLBI NIH HHS U01 HL068269NHLBI NIH HHS U01 HL068270NHLBI NIH HHS U01 HL068279NHLBI NIH HHS U01 HL068281NHLBI NIH HHS U01 HL068285NHLBI NIH HHS U01 HL068288NHLBI NIH HHS U01 HL068290NHLBI NIH HHS U01 HL068292NHLBI NIH HHS U01 HL085057NHLBI NIH HHS U10 HL068270NHLBI NIH HHS U10 HL109673NHLBI NIH HHS U10 HL109737NHLBI NIH HHS U10 HL109741NHLBI NIH HHS U10 HL109743NHLBI NIH HHS U10 HL109778NHLBI NIH HHS U10 HL109781NHLBI NIH HHS U10 HL109816
6 · The paper itself

Abstract

objectivesThe technical performance score (TPS) has been reported in a single center study to predict the outcomes after congenital cardiac surgery. We sought to determine the association of the TPS with outcomes in patients undergoing the Norwood procedure in the Single Ventricle Reconstruction trial.

methodsWe calculated the TPS (class 1, optimal; class 2, adequate; class 3, inadequate) according to the predischarge echocardiograms analyzed in a core laboratory and unplanned reinterventions that occurred before discharge from the Norwood hospitalization. Multivariable regression examined the association of the TPS with interval to first extubation, Norwood length of stay, death or transplantation, unplanned postdischarge reinterventions, and neurodevelopment at 14 months old.

resultsOf 549 patients undergoing a Norwood procedure, 356 (65%) had an echocardiogram adequate to assess atrial septal restriction or arch obstruction or an unplanned reintervention, enabling calculation of the TPS. On multivariable regression, adjusting for preoperative variables, a better TPS was an independent predictor of a shorter interval to first extubation (P=.019), better transplant-free survival before Norwood discharge (P<.001; odds ratio, 9.1 for inadequate vs optimal), shorter hospital length of stay (P<.001), fewer unplanned reinterventions between Norwood discharge and stage II (P=.004), and a higher Bayley II psychomotor development index at 14 months (P=.031). The TPS was not associated with transplant-free survival after Norwood discharge, unplanned reinterventions after stage II, or the Bayley II mental development index at 14 months.

conclusionsTPS is an independent predictor of important outcomes after Norwood and could serve as a tool for quality improvement.

Indexed as

Decision Support TechniquesChild DevelopmentChi-Square DistributionDatabases, FactualEchocardiographyHeart Defects, CongenitalHeart TransplantationHumansInfantKaplan-Meier EstimateLength of StayMultivariate AnalysisNeuropsychological TestsNorth AmericaNorwood ProceduresOdds Ratio

Identifiers

PMID25037617
PMCPMC4253672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.