Evidence map›Paper›PMID 25037158›Full record

ReviewCellular and molecular life sciences : CMLS2014

Metabolic circuits in neural stem cells.

Do-Yeon Kim, Inmoo Rhee, Jihye Paik

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Molecular autism · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Stem Cell Metabolism and Diet.Current stem cell reports · 2020
    Article
  16. Article
  17. Metabolic regulation of neurodifferentiation in the adult brain.Cellular and molecular life sciences : CMLS · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Do-Yeon KimDepartment of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York City, NY, 10065, USA.
Inmoo Rhee
Jihye Paik

Funding

The Mechanisms Underlying How Oxidative Stress Influences Neural Stem Cell FateR01AG048284 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI PAIK, JIHYE · 2014 to 2018
$1.7M
NIA NIH HHS R01 AG048284
6 · The paper itself

Abstract

Metabolic activity indicative of cellular demand is emerging as a key player in cell fate decision. Numerous studies have demonstrated that diverse metabolic pathways have a critical role in the control of the proliferation, differentiation and quiescence of stem cells. The identification of neural stem/progenitor cells (NSPCs) and the characterization of their development and fate decision process have provided insight into the regenerative potential of the adult brain. As a result, the potential of NSPCs in cell replacement therapies for neurological diseases is rapidly growing. The aim of this review is to discuss the recent findings on the crosstalk among key regulators of NSPC development and the metabolic regulation crucial for the function and cell fate decisions of NSPCs. Fundamental understanding of the metabolic circuits in NSPCs may help to provide novel approaches for reactivating neurogenesis to treat degenerative brain conditions and cognitive decline.

Indexed as

Gene Expression RegulationAnimalsBrainCell LineageCognitionCognition DisordersEpigenesis, GeneticHumansHypoxiaInflammationLipidsNeural Stem CellsNeurodegenerative DiseasesNeurogenesisRegenerationLipids

Identifiers

PMID25037158
PMCPMC4394599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.