Evidence map›Paper›PMID 25037112›Full record

ArticleHeart and vessels2015

Impact of thin-cap fibroatheroma on predicting deteriorated coronary flow during interventional procedures in acute as well as stable coronary syndromes: insights from optical coherence tomography analysis.

Tadatsugu Gamou, Kenji Sakata, Takao Matsubara, Toshihiko Yasuda, Kenji Miwa, Masaru Inoue, Honin Kanaya, Tetsuo Konno, Kenshi Hayashi, Masaaki Kawashiri and 1 more

Abstract read
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Article in Heart and vessels, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tadatsugu GamouDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
Kenji SakataDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
Takao MatsubaraDepartment of Cardiology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Toshihiko YasudaDepartment of Cardiology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Kenji MiwaDepartment of Cardiology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Masaru InoueDepartment of Cardiology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Honin KanayaDepartment of Cardiology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Tetsuo KonnoDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
Kenshi HayashiDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
Masaaki KawashiriDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
Masakazu YamagishiDivision of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan. myamagi@med.kanazawa-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence of deteriorated coronary flow associated with distal embolization during percutaneous coronary intervention results in impaired myocardial perfusion and worsens the clinical prognosis. This study aimed to examine the impact of optical coherence tomography (OCT)-determined coronary plaque morphology on the prediction of deteriorated coronary flow after stent implantation in acute as well as stable coronary syndromes (ACS and SAP, respectively). We studied 126 patients who underwent OCT during stenting for ACS (n = 44) and SAP (n = 82) with a de novo lesion. Angiographic deteriorated coronary flow was defined as the deterioration of TIMI flow grade after mechanical dilatation in the absence of a mechanical obstruction on angiograms. Patients could be divided into the deteriorated flow group (n = 21) and the reflow group (n = 105). Under these conditions, the presence of thin-cap fibroatheroma (TCFA) was more frequently observed in the deteriorated flow group than in the reflow group in both ACS and SAP. A multivariable logistic regression model revealed that TCFA was an independent predictor of deteriorated coronary flow (hazard ratio: 12.32; 95 % confidence interval: 3.02-50.31; p = 0.0005). These results demonstrate that TCFA detected by OCT could be a strong predictor of the occurrence of deteriorated coronary flow during stent implantation in ACS as well as SAP.

Indexed as

StentsAcute Coronary SyndromeAgedAngina, StableCoronary AngiographyFemaleHeartHumansJapanLogistic ModelsMaleMiddle AgedMultivariate AnalysisPercutaneous Coronary InterventionPlaque, AtheroscleroticPredictive Value of TestsAcute coronary syndromeNo-reflow phenomenonOptical coherence tomographyPercutaneous coronary interventionStable angina

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.