Evidence map›Paper›PMID 25035858›Full record

ArticleInternational journal of molecular and cellular medicine2014

Fetal Vegf Genotype is More Important for Abortion Risk than Mother Genotype.

Sinem Atik Yalcintepe, Fatma Silan, Servet Ozden Hacivelioglu, Ahmet Uludag, Emine Cosar, Ozturk Ozdemir

Open access · greenAbstract read
In one paragraph

Article in International journal of molecular and cellular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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  10. Association of Growth Factors Genes with Miscarriage.Journal of reproduction & infertility
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sinem Atik YalcintepeDepartment of Medical Genetics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Fatma SilanDepartment of Medical Genetics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Servet Ozden HaciveliogluDepartment of Gynecology and Obstetrics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Ahmet UludagDepartment of Medical Genetics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Emine CosarDepartment of Gynecology and Obstetrics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Ozturk OzdemirDepartment of Medical Genetics, School of Medicine, Canakkale On Sekiz Mart University, Canakkale, Turkey.
Çanakkale Onsekiz Mart Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VEGF gene has been reported to be related with many diseases and recurrent pregnancy loss in various studies. Concerning the role of VEGF polymorphisms in pregnancy losses, generally mothers genotypes have been analyzed. To evaluate the association between VEGF A +405G/C (rs2010963), -460T/C (rs833061), +936C/T (rs3025039) and - 2578A/C (rs699947) polymorphisms and spontaneous abortion, we studied the genotypes of spontaneously aborted fetuses, their mothers and healthy controls. 23 spontaneously aborted fetal materials, 22 mothers who had these abortions and 86 healthy controls were included in this study. rs2010963, rs833061, rs3025039 and rs699947 polymorphisms were analyzed by Real Time PCR technique after genomic DNA isolation from all subjects. The frequencies of VEGF A rs2010963 GG genotype and rs2010963 G allele were higher in fetuses compared both with mothers and healthy controls. VEGF A rs3025039 TT genotype and rs3025039 T allele frequencies were higher in fetuses comparing with mothers. VEGF A rs833061 CT and TT genotypes frequencies were higher in fetuses comparing with mothers. We ascertained that VEGF A rs2010963, rs833061 and rs3025039 are the risk factors for spontaneous abortion in fetal genotypes comparing with their mothers and healthy controls.

Indexed as

fetussingle nucleotide polymorphismSpontaneous abortionVEGF

Identifiers

PMID25035858
PMCPMC4082810
OpenAlexW2156931207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.