Evidence map›Paper›PMID 25035812›Full record

ArticleJournal of molecular biomarkers & diagnosis2013

Bronchoalveolar Lavage Fluid Utilized Ex Vivo to Validate In Vivo Findings: Inhibition of Gap Junction Activity in Lung Tumor Promotion is Toll-Like Receptor 4-Dependent.

Thomas Hill, Ross S Osgood, Kalpana Velmurugan, Carla-Maria Alexander, Brad L Upham, Alison K Bauer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of molecular biomarkers & diagnosis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thomas HillDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
Ross S OsgoodDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
Kalpana VelmuruganDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
Carla-Maria AlexanderDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
Brad L UphamDepartment of Pediatrics and Human Development, Michigan State University, Lansing, USA.
Alison K BauerDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
University of Colorado Anschutz Medical Campus · US

Funding

Epigenetic toxicity of polycyclic aromatic hydrocarbonsR01ES013268 · NIEHS · MICHIGAN STATE UNIVERSITY · PI UPHAM, BRAD L. · 2006 to 2008
$1.1M
Epigenetic toxicity of polycyclicaromatic hydrocarbonsR56ES013268 · NIEHS · MICHIGAN STATE UNIVERSITY · PI UPHAM, BRAD L. · 2005 to 2005
$182k
NIEHS NIH HHS R01 ES013268NIEHS NIH HHS R56 ES013268
6 · The paper itself

Abstract

TLR4 protects against lung tumor promotion and pulmonary inflammation in mice. Connexin 43 (Cx43), a gap junction gene, was increased in

Indexed as

Bronchoalveolar Lavage Fluid (BALF)Butylated Hydroxytoluene (BHT)Connexin 43 (cx43)Gap Junction Intercellular Communication (GJIC)Gap junctionsLungToll-like receptor 4 (TLR4)Tumor Promotion

Identifiers

PMID25035812
PMCPMC4098145
OpenAlexW2152981737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.