Evidence map›Paper›PMID 25035784›Full record

ArticleInternational journal of clinical and experimental medicine2014

Serum paraoxonase, TAS, TOS and ceruloplasmin in brucellosis.

Ozlem Demirpençe, Bünyamin Sevim, Mustafa Yıldırım, Nilhan Ayan Nurlu, Duygu Mert, Osman Evliyaoğlu

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Hyperbaric oxygen treatment ameliorates lung injury in paraquat intoxicated rats.International journal of clinical and experimental pathology · 2015
    Article
  9. Expression of eosinophils be beneficial to early clinical diagnosis of brucellosis.International journal of clinical and experimental medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ozlem DemirpençeDepartment of Biochemistry, Dicle University Faculty of Medicine Diyarbakır, Turkey.
Bünyamin SevimDepartment of Biochemistry, Dicle University Faculty of Medicine Diyarbakır, Turkey.
Mustafa YıldırımDepartment of Medical Oncology, Ministry of Health Batman Regional Govermant Hospital Batman, Turkey.
Nilhan Ayan NurluDepartment of Biochemistry, Ministry of Health Gaziosmanpaşa Taksim Education and Research Hospital Istanbul Turkey.
Duygu MertDepartment Enfection Disease and Clinical Microbiology, Ministry of Health Batman Regional Govermant Hospital Batman, Turkey.
Osman EvliyaoğluDepartment of Biochemistry, Dicle University Faculty of Medicine Diyarbakır, Turkey.
Dicle University · TRBatman University · TRGaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledIt is possible that brucellosis may be related to increase free radical production and antioxidant depletion. Thus, in the present study we aimed to evaluate the oxidative status in patient with brucellosis and healthy controls.

methodsThis study includes the patients with brucellosis diagnosed by clinical findings and positive agglutination titer. The paraoxonase, ceruloplasmin, total antioxidant capacity and total oxidant status values were measured from the samples taken. The oxidative stress index value was calculated through the total antioxidant capacity and total oxidant status values.

resultsA total number of 93 people, 40 women (43%) and 53 men (57%) were included to the study. The levels of ceruloplasmin were found higher in patients when compared to the control group (p < 0.001). The total antioxidant capacity level was found significantly higher in the patients group when compared to the control group (p < 0.001). The oxidative stress index value was significantly lower in the patients group when compared to the control group (p < 0.001). The paraoxonase-1 level was not different in control and patient groups (p = 0.077).

conclusionsBrucellosis is an infection that is frequently seen in Mediterranean countries. This infection breaks the oxidant and antioxidant balance. In this disease, oxidant-antioxidant system indicators such as ceruloplasmin, total antioxidant capacity, total oxidant status and oxidative stress index can be used for showing the role of the brucella infection and for the monitoring of the treatment results.

Indexed as

Brucellaceruloplasminparaoxonasetotal antioxidant capacitytotal oxidant status

Identifiers

PMID25035784
PMCPMC4100970
OpenAlexW1931907600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.